# MAPK activated protein kinase 2

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21132836](https://www.wikidata.org/wiki/Q21132836)  
**Source**: https://4ort.xyz/entity/mapk-activated-protein-kinase-2-q21132836


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P49137)
3. Q20641742
4. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49137)
5. [The Primary Structure of a Human Map Kinase Activated Protein Kinase 2](http://www.ebi.ac.uk/QuickGO/annotations?protein=P49137&geneProductId=UniProtKB:P49137)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49137)
7. [A comparison of the substrate specificity of MAPKAP kinase‐2 and MAPKAP kinase‐3 and their activation by cytokines and cellular stress](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49137)
8. [Stabilization of Urokinase and Urokinase Receptor mRNAs by HuR Is Linked to Its Cytoplasmic Accumulation Induced by Activated Mitogen-Activated Protein Kinase-Activated Protein Kinase 2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49137)
9. [DNA Damage Activates a Spatially Distinct Late Cytoplasmic Cell-Cycle Checkpoint Network Controlled by MK2-Mediated RNA Stabilization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49137)
10. [MK2‐induced tristetraprolin:14‐3‐3 complexes prevent stress granule association and ARE‐mRNA decay](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49137)
11. [The Protein Interaction Landscape of the Human CMGC Kinase Group](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49137)
12. [Phosphorylation of HSF1 by MAPK-Activated Protein Kinase 2 on Serine 121, Inhibits Transcriptional Activity and Promotes HSP90 Binding](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49137)
13. [Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49137)
14. [Using an in Situ Proximity Ligation Assay to Systematically Profile Endogenous Protein–Protein Interactions in a Pathway Network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49137)
15. [A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49137)
16. [Crystal Structure of the P38α-MAPKAP Kinase 2 Heterodimer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49137)
17. [MAPKAP kinase MK2 maintains self‐renewal capacity of haematopoietic stem cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49137)
18. [Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49137)
19. [Toward an understanding of the protein interaction network of the human liver](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49137)
20. [Distinct roles of MK2 and MK5 in cAMP/PKA- and stress/p38MAPK-induced heat shock protein 27 phosphorylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49137)
21. [The Primary Structure of a Human Map Kinase Activated Protein Kinase 2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49137)
22. [The substrate specificity and structure of mitogen-activated protein (MAP) kinase-activated protein kinase-2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49137)
23. [Identification of novel phosphorylation sites required for activation of MAPKAP kinase‐2.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49137)
24. [Endoplasmic reticulum-associated ubiquitin-conjugating enzyme Ube2j1 is a novel substrate of MK2 (MAPKAP kinase-2) involved in MK2-mediated TNFα production](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49137)
25. [The phosphorylation of CapZ-interacting protein (CapZIP) by stress-activated protein kinases triggers its dissociation from CapZ](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49137)
26. [Proteomic Analysis of Exosomes from Human Neural Stem Cells by Flow Field-Flow Fractionation and Nanoflow Liquid Chromatography−Tandem Mass Spectrometry](http://www.ebi.ac.uk/QuickGO/annotations?protein=P49137&geneProductId=UniProtKB:P49137)
27. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P49137&geneProductId=UniProtKB:P49137)
28. [DNA Damage Activates a Spatially Distinct Late Cytoplasmic Cell-Cycle Checkpoint Network Controlled by MK2-Mediated RNA Stabilization](http://www.ebi.ac.uk/QuickGO/annotations?protein=P49137&geneProductId=UniProtKB:P49137)
29. [The substrate specificity and structure of mitogen-activated protein (MAP) kinase-activated protein kinase-2](http://www.ebi.ac.uk/QuickGO/annotations?protein=P49137&geneProductId=UniProtKB:P49137)
30. [Proteomic Analysis of Exosomes from Human Neural Stem Cells by Flow Field-Flow Fractionation and Nanoflow Liquid Chromatography−Tandem Mass Spectrometry](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49137)
31. [MK2‐induced tristetraprolin:14‐3‐3 complexes prevent stress granule association and ARE‐mRNA decay](http://www.ebi.ac.uk/QuickGO/annotations?protein=P49137&geneProductId=UniProtKB:P49137)
32. [A comparison of the substrate specificity of MAPKAP kinase‐2 and MAPKAP kinase‐3 and their activation by cytokines and cellular stress](http://www.ebi.ac.uk/QuickGO/annotations?protein=P49137&geneProductId=UniProtKB:P49137)
33. [The phosphorylation of CapZ-interacting protein (CapZIP) by stress-activated protein kinases triggers its dissociation from CapZ](http://www.ebi.ac.uk/QuickGO/annotations?protein=P49137&geneProductId=UniProtKB:P49137)
34. [Vascular endothelial growth factor induces heat shock protein (HSP) 27 serine 82 phosphorylation and endothelial tubulogenesis via protein kinase D and independent of p38 kinase](http://www.ebi.ac.uk/QuickGO/annotations?protein=P49137&geneProductId=UniProtKB:P49137)
35. [Vascular endothelial growth factor induces heat shock protein (HSP) 27 serine 82 phosphorylation and endothelial tubulogenesis via protein kinase D and independent of p38 kinase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49137)
36. Ensembl Release 99