# major histocompatibility complex, class I, G

> mammalian proteins found in Homo sapiens

**Wikidata**: [Q3124896](https://www.wikidata.org/wiki/Q3124896)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/HLA-G)  
**Source**: https://4ort.xyz/entity/major-histocompatibility-complex-class-i-g


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P17693)
3. Q20641742
4. [Modulation of dendritic cell differentiation by HLA-G and ILT4 requires the IL-6--STAT3 signaling pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17693)
5. [Multimeric structures of HLA-G isoforms function through differential binding to LILRB receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17693)
6. [Complexes of HLA-G protein on the cell surface are important for leukocyte Ig-like receptor-1 function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17693)
7. [Multimeric structures of HLA-G isoforms function through differential binding to LILRB receptors](http://www.ebi.ac.uk/QuickGO/annotations?protein=P17693&geneProductId=UniProtKB:P17693)
8. [Soluble HLA-G inhibits myeloid dendritic cell function in HIV-1 infection by interacting with leukocyte immunoglobulin-like receptor B2](http://www.ebi.ac.uk/QuickGO/annotations?protein=P17693&geneProductId=UniProtKB:P17693)
9. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P17693&geneProductId=UniProtKB:P17693)
10. [Calreticulin associates with non‐HLA‐A,‐B class I proteins in the human choriocarcinoma cell lines JEG‐3 and BeWo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17693)
11. [The truncated cytoplasmic tail of HLA-G serves a quality-control function in post-ER compartments](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17693)
12. [A human histocompatibility leukocyte antigen (HLA)-G-specific receptor expressed on all natural killer cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17693)
13. [Activation of NK cells by an endocytosed receptor for soluble HLA-G.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17693)
14. [Soluble HLA-G1 inhibits angiogenesis through an apoptotic pathway and by direct binding to CD160 receptor expressed by endothelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17693)
15. [Human inhibitory receptors Ig-like transcript 2 (ILT2) and ILT4 compete with CD8 for MHC class I binding and bind preferentially to HLA-G](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17693)
16. [An essential function of tapasin in quality control of HLA-G molecules](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17693)
17. [Tyrosine nitration in the human leucocyte antigen-G-binding domain of the Ig-like transcript 2 protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17693)
18. [Structural basis for recognition of the nonclassical MHC molecule HLA-G by the leukocyte Ig-like receptor B2 (LILRB2/LIR2/ILT4/CD85d)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17693)
19. [A motif in LILRB2 critical for Angptl2 binding and activation.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17693)
20. [Efficient leukocyte Ig-like receptor signaling and crystal structure of disulfide-linked HLA-G dimer.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17693)
21. [Soluble HLA-G inhibits myeloid dendritic cell function in HIV-1 infection by interacting with leukocyte immunoglobulin-like receptor B2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17693)
22. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17693)
23. [The Structure and Stability of the Monomorphic HLA-G Are Influenced by the Nature of the Bound Peptide](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17693)
24. [Nonclassical HLA-G molecules are classical peptide presenters](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17693)
25. [The membrane-bound and soluble forms of HLA-G bind identical sets of endogenous peptides but differ with respect to TAP association](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17693)
26. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17693)
27. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P17693&geneProductId=UniProtKB:P17693)
28. [HLA-G2, -G3, and -G4 isoforms expressed as nonmature cell surface glycoproteins inhibit NK and antigen-specific CTL cytolysis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17693)
29. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17693)
30. [Differentiation of type 1 T regulatory cells (Tr1) by tolerogenic DC-10 requires the IL-10-dependent ILT4/HLA-G pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17693)
31. [HLA-G expression in melanoma: a way for tumor cells to escape from immunosurveillance](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17693)
32. [Binding of HLA-G to ITIM-bearing Ig-like transcript 2 receptor suppresses B cell responses](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17693)
33. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=P17693&geneProductId=UniProtKB:P17693)
34. [HLA-G homodimer-induced cytokine secretion through HLA-G receptors on human decidual macrophages and natural killer cells.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17693)
35. [Cellular senescence induced by CD158d reprograms natural killer cells to promote vascular remodeling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17693)
36. Ensembl Release 99
37. [OpenAlex](https://docs.openalex.org/download-snapshot/snapshot-data-format)