# Lysyl-tRNA synthetase 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21130495](https://www.wikidata.org/wiki/Q21130495)  
**Source**: https://4ort.xyz/entity/lysyl-trna-synthetase-1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q15046)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15046)
5. [The Human Lysyl-tRNA Synthetase Gene Encodes Both the Cytoplasmic and Mitochondrial Enzymes by Means of an Unusual Alternative Splicing of the Primary Transcript](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15046&geneProductId=UniProtKB:Q15046)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15046&geneProductId=UniProtKB:Q15046)
7. [Structural Switch of Lysyl-tRNA Synthetase between Translation and Transcription](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15046&geneProductId=UniProtKB:Q15046)
8. [Human Lysyl-tRNA Synthetase Accepts Nucleotide 73 Variants and Rescues Escherichia coli Double-defective Mutant](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15046&geneProductId=UniProtKB:Q15046)
9. [Reinvestigation of Aminoacyl-TRNA Synthetase Core Complex by Affinity Purification-Mass Spectrometry Reveals TARSL2 as a Potential Member of the Complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15046)
10. [Structural Switch of Lysyl-tRNA Synthetase between Translation and Transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15046)
11. [Structural context for mobilization of a human tRNA synthetase from its cytoplasmic complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15046)
12. [A Directed Protein Interaction Network for Investigating Intracellular Signal Transduction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15046)
13. [LuTHy: a double‐readout bioluminescence‐based two‐hybrid technology for quantitative mapping of protein–protein interactions in mammalian cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15046)
14. [Chemical inhibition of prometastatic lysyl-tRNA synthetase–laminin receptor interaction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15046)
15. [Towards a proteome-scale map of the human protein–protein interaction network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15046)
16. [A Proteome-Scale Map of the Human Interactome Network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15046)
17. [Phosphorylation of glutamyl-prolyl tRNA synthetase by cyclin-dependent kinase 5 dictates transcript-selective translational control](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15046)
18. [Coding Region Polyadenylation Generates a Truncated tRNA Synthetase that Counters Translation Repression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15046)
19. [Toward an understanding of the protein interaction network of the human liver](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15046)
20. [Characterization of the interaction between lysyl‐tRNA synthetase and laminin receptor by NMR](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15046)
21. [Crystal structure of tetrameric form of human lysyl-tRNA synthetase: Implications for multisynthetase complex formation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15046)
22. [The Human Lysyl-tRNA Synthetase Gene Encodes Both the Cytoplasmic and Mitochondrial Enzymes by Means of an Unusual Alternative Splicing of the Primary Transcript](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15046)
23. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15046)
24. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15046&geneProductId=UniProtKB:Q15046)
25. [Human Lysyl-tRNA Synthetase Accepts Nucleotide 73 Variants and Rescues Escherichia coli Double-defective Mutant](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15046)
26. [Human lysyl-tRNA synthetase is secreted to trigger proinflammatory response](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15046&geneProductId=UniProtKB:Q15046)
27. [Dissection of the Structural Organization of the Aminoacyl-tRNA Synthetase Complex](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15046&geneProductId=UniProtKB:Q15046)
28. [Dynamic Organization of Aminoacyl-tRNA Synthetase Complexes in the Cytoplasm of Human Cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15046&geneProductId=UniProtKB:Q15046)
29. [Human lysyl-tRNA synthetase is secreted to trigger proinflammatory response](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15046)
30. [Dynamic Organization of Aminoacyl-tRNA Synthetase Complexes in the Cytoplasm of Human Cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15046)
31. [Dissection of the Structural Organization of the Aminoacyl-tRNA Synthetase Complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15046)
32. [LysRS Serves as a Key Signaling Molecule in the Immune Response by Regulating Gene Expression](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15046&geneProductId=UniProtKB:Q15046)
33. [LysRS Serves as a Key Signaling Molecule in the Immune Response by Regulating Gene Expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15046)
34. Ensembl Release 99