# Lysyl oxidase

> mammalian protein found in Mus musculus

**Wikidata**: [Q14907100](https://www.wikidata.org/wiki/Q14907100)  
**Source**: https://4ort.xyz/entity/lysyl-oxidase-q14907100


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P28301)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28301)
5. [Lysyl oxidase binds transforming growth factor-beta and regulates its signaling via amine oxidase activity.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28301)
6. [Fibulin-4 conducts proper elastogenesis via interaction with cross-linking enzyme lysyl oxidase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28301)
7. [The Pro-regions of lysyl oxidase and lysyl oxidase-like 1 are required for deposition onto elastic fibers](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28301)
8. [The Ras signaling inhibitor LOX-PP interacts with Hsp70 and c-Raf to reduce Erk activation and transformed phenotype of breast cancer cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28301)
9. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P28301&geneProductId=UniProtKB:P28301)
10. [Loss of function mutation in LOX causes thoracic aortic aneurysm and dissection in humans](http://www.ebi.ac.uk/QuickGO/annotations?protein=P28301&geneProductId=UniProtKB:P28301)
11. [Lysyl oxidase deficiency in lung and fibroblasts from mice with hereditary emphysema](http://www.ebi.ac.uk/QuickGO/annotations?protein=P28301&geneProductId=UniProtKB:P28301)
12. [Up-regulation and altered distribution of lysyl oxidase in the central nervous system of mutant SOD1 transgenic mouse model of amyotrophic lateral sclerosis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P28301&geneProductId=UniProtKB:P28301)
13. [Lysyl oxidase is essential for normal development and function of the respiratory system and for the integrity of elastic and collagen fibers in various tissues](http://www.ebi.ac.uk/QuickGO/annotations?protein=P28301&geneProductId=UniProtKB:P28301)
14. [Decreased lysyl oxidase activity in the aneurysm-prone, mottled mouse](http://www.ebi.ac.uk/QuickGO/annotations?protein=P28301&geneProductId=UniProtKB:P28301)
15. [Loss of function mutation in LOX causes thoracic aortic aneurysm and dissection in humans](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28301)
16. [Up-regulation and altered distribution of lysyl oxidase in the central nervous system of mutant SOD1 transgenic mouse model of amyotrophic lateral sclerosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28301)
17. [Lysyl oxidase deficiency in lung and fibroblasts from mice with hereditary emphysema](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28301)
18. [Decreased lysyl oxidase activity in the aneurysm-prone, mottled mouse](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28301)
19. [Lysyl oxidase is essential for normal development and function of the respiratory system and for the integrity of elastic and collagen fibers in various tissues](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28301)
20. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28301)
21. [Transient expression of lysyl oxidase by liver myofibroblasts in murine schistosomiasis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28301)
22. [Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c](http://www.ebi.ac.uk/QuickGO/annotations?protein=P28301&geneProductId=UniProtKB:P28301)
23. [Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28301)
24. [Muscle composition is regulated by a Lox-TGFβ feedback loop](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28301)
25. [Extracellular-matrix gene expression during mouse submandibular gland development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28301)
26. [The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28301)
27. [Global genetic analysis in mice unveils central role for cilia in congenital heart disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28301)
28. [Inactivation of the lysyl oxidase gene Lox leads to aortic aneurysms, cardiovascular dysfunction, and perinatal death in mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28301)
29. [Mitochondrial production of reactive oxygen species and incidence of age-associated lymphoma in OF1 mice: effect of alternate-day fasting](http://www.ebi.ac.uk/QuickGO/annotations?protein=P28301&geneProductId=UniProtKB:P28301)
30. [Inactivation of the lysyl oxidase gene Lox leads to aortic aneurysms, cardiovascular dysfunction, and perinatal death in mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=P28301&geneProductId=UniProtKB:P28301)
31. [Lysyl oxidase activity contributes to collagen stabilization during liver fibrosis progression and limits spontaneous fibrosis reversal in mice.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28301)
32. [Increased Aortic Stiffness and Attenuated Lysyl Oxidase Activity in Obesity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28301)
33. [Lysyl oxidase (lox) gene deficiency affects osteoblastic phenotype.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28301)
34. [Mex3a Marks a Slowly Dividing Subpopulation of Lgr5+ Intestinal Stem Cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28301)
35. [Lysyl oxidase oxidizes cell membrane proteins and enhances the chemotactic response of vascular smooth muscle cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P28301&geneProductId=UniProtKB:P28301)
36. [Mechanical behavior and matrisome gene expression in the aneurysm-prone thoracic aorta of newborn lysyl oxidase knockout mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28301)
37. [Downregulation of Lysyl Oxidase Protects Retinal Endothelial Cells From High Glucose-Induced Apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28301)
38. [Control of megakaryocyte expansion and bone marrow fibrosis by lysyl oxidase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28301)
39. [Targeting lysyl oxidase reduces peritoneal fibrosis.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28301)
40. [Lysyl oxidase oxidizes cell membrane proteins and enhances the chemotactic response of vascular smooth muscle cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28301)
41. ensembl Release 106