Lysosomal trafficking regulator
type: Thing
description: mammalian protein found in Homo sapiens
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P352
  value: Fritz Sturm
additional property: PropertyValue
  property ID: P361
  value: WD40/YVTN repeat-like-containing domain superfamily
additional property: PropertyValue
  property ID: P361
  value: BEACH domain superfamily
additional property: PropertyValue
  property ID: P361
  value: Armadillo-type fold
additional property: PropertyValue
  property ID: P527
  value: WD40 repeat
additional property: PropertyValue
  property ID: P527
  value: BEACH domain
additional property: PropertyValue
  property ID: P527
  value: PH-BEACH domain
additional property: PropertyValue
  property ID: P637
  value: NP_000072
additional property: PropertyValue
  property ID: P637
  value: NP_001288294
additional property: PropertyValue
  property ID: P637
  value: XP_011542333
additional property: PropertyValue
  property ID: P680
  value: protein binding
additional property: PropertyValue
  property ID: P681
  value: cytoplasm
additional property: PropertyValue
  property ID: P681
  value: microtubule cytoskeleton
additional property: PropertyValue
  property ID: P682
  value: protein transport
additional property: PropertyValue
  property ID: P682
  value: pigmentation
additional property: PropertyValue
  property ID: P682
  value: melanosome organization
additional property: PropertyValue
  property ID: P702
  value: LYST
additional property: PropertyValue
  property ID: P703
  value: Homo sapiens
additional property: PropertyValue
  property ID: P705
  value: ENSP00000374443
additional property: PropertyValue
  property ID: P705
  value: ENSP00000374444
additional property: PropertyValue
  property ID: P705
  value: ENSP00000417168
confidence:
  popularity graph score:
    score: 0.001
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 9
      unique citations norm: 0.004
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 9
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: Q99698
    source count: 1
    confidence: 0.2
    value label: Fritz Sturm
  P361:
    value: Q24784804
    source count: 1
    confidence: 0.2
    value label: WD40/YVTN repeat-like-containing domain superfamily
  P361:
    value: Q41797486
    source count: 1
    confidence: 0.2
    value label: BEACH domain superfamily
  P361:
    value: Q24780424
    source count: 1
    confidence: 0.2
    value label: Armadillo-type fold
  P361:
    value: Q41797440
    source count: 1
    confidence: 0.2
    value label: WD40-repeat-containing domain superfamily
  P361:
    value: Q24773537
    source count: 1
    confidence: 0.2
    value label: Lysosomal-trafficking regulator
  P527:
    value: Q7948257
    source count: 1
    confidence: 0.2
    value label: WD40 repeat
  P527:
    value: Q24777194
    source count: 1
    confidence: 0.2
    value label: BEACH domain
  P527:
    value: Q24778320
    source count: 1
    confidence: 0.2
    value label: PH-BEACH domain
  P527:
    value: Q24777393
    source count: 1
    confidence: 0.2
    value label: WD40 repeat, conserved site
  P637:
    value: NP_000072
    source count: 1
    confidence: 0.2
  P637:
    value: NP_001288294
    source count: 1
    confidence: 0.2
  P637:
    value: XP_011542333
    source count: 1
    confidence: 0.2
  P637:
    value: XP_011542334
    source count: 1
    confidence: 0.2
  P637:
    value: XP_011542335
    source count: 1
    confidence: 0.2
  P680:
    value: Q167149
    source count: 1
    confidence: 0.2
    value label: protein binding
  P681:
    value: Q79899
    source count: 1
    confidence: 0.2
    value label: cytoplasm
  P681:
    value: Q14888122
    source count: 1
    confidence: 0.2
    value label: microtubule cytoskeleton
  P682:
    value: Q14860325
    source count: 1
    confidence: 0.2
    value label: protein transport
  P682:
    value: Q14863538
    source count: 1
    confidence: 0.2
    value label: pigmentation
  P682:
    value: Q15313754
    source count: 1
    confidence: 0.2
    value label: melanosome organization
  P682:
    value: Q21111445
    source count: 1
    confidence: 0.2
    value label: endosome to lysosome transport via multivesicular body sorting pathway
  P682:
    value: Q14902472
    source count: 1
    confidence: 0.2
    value label: lysosome organization

value: Q4392057
source count: 1
confidence: 0.2
value label: LYST

value: Q15978631
source count: 1
confidence: 0.2
value label: Homo sapiens

value: ENSP00000374443
source count: 1
confidence: 0.2

value: ENSP00000374444
source count: 1
confidence: 0.2

value: ENSP00000417168
source count: 1
confidence: 0.2

source: The Chediak-Higashi protein interacts with SNARE complex and signal transduction proteins
stated in qid: Q24296289
retrieved: 2019-04-08

source: GOA
stated in qid: Q28018111
retrieved: 2019-04-08

source: Deficient peptide loading and MHC class II endosomal sorting in a human genetic immunodeficiency disease: the Chediak-Higashi syndrome
stated in qid: Q24320302
retrieved: 2019-04-08

source: Protein truncation test of LYST reveals heterogenous mutations in patients with Chediak-Higashi syndrome
stated in qid: Q22011161
retrieved: 2019-04-08

source: Chediak-Higashi gene in humans. I. Impairment of natural - killer function
stated in qid: Q24300801
retrieved: 2019-04-08

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2019-11-13

source: Q20641742
stated in qid: Q20641742
retrieved: 2020-05-30

source: Ensembl Release 99
stated in qid: Q83867711

wikidata id: Q21122356
domain: protein
level: standard
html url: https://4ort.xyz/entity/lysosomal-trafficking-regulator
markdown url: https://4ort.xyz/entity/lysosomal-trafficking-regulator.md
facts url summary: https://4ort.xyz/entity/lysosomal-trafficking-regulator/facts.json
facts url standard: https://4ort.xyz/entity/lysosomal-trafficking-regulator/facts.json
facts url full: https://4ort.xyz/entity/lysosomal-trafficking-regulator/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-24T08:52:58.455782Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T13:58:50.900290+00:00Z