Lysine ketoglutarate reductase/saccharopine dehydrogenase Dmel_CG7144
type: Thing
description: protein found in Drosophila melanogaster
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P361
  value: NAD(P)-binding domain superfamily
additional property: PropertyValue
  property ID: P361
  value: Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain, protein family
additional property: PropertyValue
  property ID: P361
  value: Saccharopine dehydrogenase, NADP binding domain, protein family
additional property: PropertyValue
  property ID: P527
  value: Saccharopine dehydrogenase, NADP binding domain
additional property: PropertyValue
  property ID: P527
  value: Saccharopine dehydrogenase, C-terminal
additional property: PropertyValue
  property ID: P527
  value: Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal
additional property: PropertyValue
  property ID: P637
  value: NP_001285719
additional property: PropertyValue
  property ID: P637
  value: NP_609150
additional property: PropertyValue
  property ID: P680
  value: saccharopine dehydrogenase activity
additional property: PropertyValue
  property ID: P680
  value: oxidoreductase activity
additional property: PropertyValue
  property ID: P681
  value: cytoplasm
additional property: PropertyValue
  property ID: P682
  value: generation of precursor metabolites and energy
additional property: PropertyValue
  property ID: P682
  value: lysine biosynthetic process via aminoadipic acid
additional property: PropertyValue
  property ID: P682
  value: regulation of histone methylation
additional property: PropertyValue
  property ID: P702
  value: LKRSDH
additional property: PropertyValue
  property ID: P703
  value: Drosophila melanogaster
additional property: PropertyValue
  property ID: P705
  value: FBpp0310050
additional property: PropertyValue
  property ID: P705
  value: FBpp0079118
confidence:
  popularity graph score:
    score: 0.001
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 7
      unique citations norm: 0.003
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 7
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: Q9VLX0
    source count: 1
    confidence: 0.2
  P361:
    value: Q41797412
    source count: 1
    confidence: 0.2
    value label: NAD(P)-binding domain superfamily
  P361:
    value: Q83132700
    source count: 1
    confidence: 0.2
    value label: Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain, protein family
  P361:
    value: Q83137695
    source count: 1
    confidence: 0.2
    value label: Saccharopine dehydrogenase, NADP binding domain, protein family
  P361:
    value: Q83135282
    source count: 1
    confidence: 0.2
    value label: Saccharopine dehydrogenase, C-terminal domain, protein family
  P361:
    value: Q83133955
    source count: 1
    confidence: 0.2
    value label: Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal domain, protein family
  P527:
    value: Q24741964
    source count: 1
    confidence: 0.2
    value label: Saccharopine dehydrogenase, NADP binding domain
  P527:
    value: Q24724813
    source count: 1
    confidence: 0.2
    value label: Saccharopine dehydrogenase, C-terminal
  P527:
    value: Q24722819
    source count: 1
    confidence: 0.2
    value label: Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal
  P527:
    value: Q24720536
    source count: 1
    confidence: 0.2
    value label: Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain
  P637:
    value: NP_001285719
    source count: 1
    confidence: 0.2
  P637:
    value: NP_609150
    source count: 1
    confidence: 0.2
  P680:
    value: Q22319819
    source count: 1
    confidence: 0.2
    value label: saccharopine dehydrogenase activity
  P680:
    value: Q14349613
    source count: 2
    confidence: 0.4
    value label: oxidoreductase activity
  P681:
    value: Q79899
    source count: 1
    confidence: 0.2
    value label: cytoplasm
  P682:
    value: Q14819781
    source count: 1
    confidence: 0.2
    value label: generation of precursor metabolites and energy
  P682:
    value: Q21468587
    source count: 1
    confidence: 0.2
    value label: lysine biosynthetic process via aminoadipic acid
  P682:
    value: Q14908011
    source count: 1
    confidence: 0.2
    value label: regulation of histone methylation
  P682:
    value: Q21130991
    source count: 1
    confidence: 0.2
    value label: histone arginine methylation
  P702:
    value: Q29734083
    source count: 1
    confidence: 0.2
    value label: LKRSDH
  P703:
    value: Q130888
    source count: 1
    confidence: 0.2
    value label: Drosophila melanogaster
  P705:
    value: FBpp0310050
    source count: 1
    confidence: 0.2
  P705:
    value: FBpp0079118
    source count: 1
    confidence: 0.2
citations:
  source: GOA
  stated in qid: Q28018111
  retrieved: 2018-07-16
citations:
  source: GOA
  stated in qid: Q28018111
  retrieved: 2019-04-08

source: dLKR/SDH regulates hormone-mediated histone arginine methylation and transcription of cell death genes
stated in qid: Q36817879
retrieved: 2019-04-08

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2022-05-25

source: Q20641742
stated in qid: Q20641742
retrieved: 2022-03-20

source: ensembl Release 106
stated in qid: Q111699881

wikidata id: Q29820943
domain: protein
level: standard
html url: https://4ort.xyz/entity/lysine-ketoglutarate-reductase-saccharopine-dehydrogenase-dmel-cg7144
markdown url: https://4ort.xyz/entity/lysine-ketoglutarate-reductase-saccharopine-dehydrogenase-dmel-cg7144.md
facts url summary: https://4ort.xyz/entity/lysine-ketoglutarate-reductase-saccharopine-dehydrogenase-dmel-cg7144/facts.json
facts url standard: https://4ort.xyz/entity/lysine-ketoglutarate-reductase-saccharopine-dehydrogenase-dmel-cg7144/facts.json
facts url full: https://4ort.xyz/entity/lysine-ketoglutarate-reductase-saccharopine-dehydrogenase-dmel-cg7144/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-09T17:48:42.254129Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T13:48:31.873729+00:00Z