# Lysine demethylase 5B

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21113093](https://www.wikidata.org/wiki/Q21113093)  
**Source**: https://4ort.xyz/entity/lysine-demethylase-5b


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q9UGL1)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UGL1)
5. [DNA-binding properties of ARID family proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UGL1)
6. [Human PLU-1 Has transcriptional repression properties and interacts with the developmental transcription factors BF-1 and PAX9](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UGL1)
7. [A novel gene (PLU-1) containing highly conserved putative DNA/chromatin binding motifs is specifically up-regulated in breast cancer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UGL1)
8. [JARID1B is a luminal lineage-driving oncogene in breast cancer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UGL1)
9. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UGL1&geneProductId=UniProtKB:Q9UGL1)
10. [The flexible loop L1 of the H3K4 demethylase JARID1B ARID domain has a crucial role in DNA-binding activity](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UGL1&geneProductId=UniProtKB:Q9UGL1)
11. [Phosphorylation of histone H3T6 by PKCbeta(I) controls demethylation at histone H3K4](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UGL1&geneProductId=UniProtKB:Q9UGL1)
12. [The flexible loop L1 of the H3K4 demethylase JARID1B ARID domain has a crucial role in DNA-binding activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UGL1)
13. [Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UGL1)
14. [Structural analysis of human KDM5B guides histone demethylase inhibitor development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UGL1)
15. [The PHD1 finger of KDM5B recognizes unmodified H3K4 during the demethylation of histone H3K4me2/3 by KDM5B](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UGL1)
16. [JARID1B is a histone H3 lysine 4 demethylase up-regulated in prostate cancer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UGL1)
17. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UGL1&geneProductId=UniProtKB:Q9UGL1)
18. [Phosphorylation of histone H3T6 by PKCbeta(I) controls demethylation at histone H3K4](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UGL1)
19. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UGL1)
20. [A novel gene (PLU-1) containing highly conserved putative DNA/chromatin binding motifs is specifically up-regulated in breast cancer](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UGL1&geneProductId=UniProtKB:Q9UGL1)
21. [Human PLU-1 Has transcriptional repression properties and interacts with the developmental transcription factors BF-1 and PAX9](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UGL1&geneProductId=UniProtKB:Q9UGL1)
22. ensembl Release 92
23. UMLS 2023