# Lysine acetyltransferase 2B

> mammalian protein found in Homo sapiens

**Wikidata**: [Q7118491](https://www.wikidata.org/wiki/Q7118491)  
**Source**: https://4ort.xyz/entity/lysine-acetyltransferase-2b


## References

1. UniProt
2. IUPHAR/BPS Guide to PHARMACOLOGY
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q92831)
4. Q20641742
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831)
6. [A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831)
7. [A WW domain protein TAZ is a critical coactivator for TBX5, a transcription factor implicated in Holt-Oram syndrome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831)
8. [KAT2A/KAT2B-targeted acetylome reveals a role for PLK4 acetylation in preventing centrosome amplification](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831)
9. [Acetylation Stabilizes ATP-Citrate Lyase to Promote Lipid Biosynthesis and Tumor Growth](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831)
10. [Site-specific acetylation of the fetal globin activator NF-E4 prevents its ubiquitination and regulates its interaction with the histone deacetylase, HDAC1.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831)
11. [Acetylation of TBX5 by KAT2B and KAT2A regulates heart and limb development.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831)
12. [Histone acetyltransferase-dependent chromatin remodeling and the vascular clock](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831)
13. [Regulation of E2A activities by histone acetyltransferases in B lymphocyte development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831)
14. [Interaction of EVI1 with cAMP-responsive element-binding protein-binding protein (CBP) and p300/CBP-associated factor (P/CAF) results in reversible acetylation of EVI1 and in co-localization in nuclear speckles](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831)
15. [BubR1 acetylation at prometaphase is required for modulating APC/C activity and timing of mitosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831)
16. [p66alpha and p66beta of the Mi-2/NuRD complex mediate MBD2 and histone interaction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831)
17. [NIR is a novel INHAT repressor that modulates the transcriptional activity of p53.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831)
18. [E1A directly binds and regulates the P/CAF acetyltransferase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831)
19. [Kruppel-like factor 2 (KLF2) regulates proinflammatory activation of monocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831)
20. [The adenovirus E1A oncoprotein recruits the cellular TRRAP/GCN5 histone acetyltransferase complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831)
21. [Histone deacetylase inhibitors repress the transactivation potential of hypoxia-inducible factors independently of direct acetylation of HIF-alpha](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831)
22. [Twist and p53 reciprocally regulate target genes via direct interaction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831)
23. [H3K9 histone methyltransferase G9a-mediated transcriptional activation of p21](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831)
24. [Interaction of the HPV E7 proteins with the pCAF acetyltransferase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831)
25. [Histone-like TAFs within the PCAF histone acetylase complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831)
26. [Glucocorticoid-stimulated preadipocyte differentiation is mediated through acetylation of C/EBPbeta by GCN5](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831)
27. [Sir2 regulates skeletal muscle differentiation as a potential sensor of the redox state](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831)
28. [Cell density‐dependent acetylation of ΔNp63α is associated with p53‐dependent cell cycle arrest](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831)
29. [SIRT2 induces the checkpoint kinase BubR1 to increase lifespan](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831)
30. [A role of DNA-PK for the metabolic gene regulation in response to insulin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831)
31. [hSirT1-dependent regulation of the PCAF-E2F1-p73 apoptotic pathway in response to DNA damage](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831)
32. [PCAF modulates PTEN activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831)
33. [Nuclear myosin 1c facilitates the chromatin modifications required to activate rRNA gene transcription and cell cycle progression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831)
34. [SIRT1 promotes cell survival under stress by deacetylation-dependent deactivation of poly(ADP-ribose) polymerase 1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831)
35. [Estrogen induces expression of BCAS3, a novel estrogen receptor-alpha coactivator, through proline-, glutamic acid-, and leucine-rich protein-1 (PELP1)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831)
36. [HNF1beta/TCF2 mutations impair transactivation potential through altered co-regulator recruitment](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831)
37. [A histone H2A deubiquitinase complex coordinating histone acetylation and H1 dissociation in transcriptional regulation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92831&geneProductId=UniProtKB:Q92831)
38. [Modulation of histone acetyltransferase activity through interaction of epstein-barr nuclear antigen 3C with prothymosin alpha](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831)
39. [Site-specific acetylation of the fetal globin activator NF-E4 prevents its ubiquitination and regulates its interaction with the histone deacetylase, HDAC1.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92831&geneProductId=UniProtKB:Q92831)
40. [A histone H2A deubiquitinase complex coordinating histone acetylation and H1 dissociation in transcriptional regulation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831)
41. [Structure and ligand of a histone acetyltransferase bromodomain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831)
42. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92831&geneProductId=UniProtKB:Q92831)
43. [Human ATAC Is a GCN5/PCAF-containing acetylase complex with a novel NC2-like histone fold module that interacts with the TATA-binding protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92831)
44. Ensembl Release 99