# Lymphocyte cytosolic protein 2

> mammalian protein found in Homo sapiens

**Wikidata**: [Q6708256](https://www.wikidata.org/wiki/Q6708256)  
**Source**: https://4ort.xyz/entity/lymphocyte-cytosolic-protein-2


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q13094)
3. Q20641742
4. [ARAP, a Novel Adaptor Protein, Is Required for TCR Signaling and Integrin-Mediated Adhesion](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13094)
5. [Distinct Binding Modes of Two Epitopes in Gab2 that Interact with the SH3C Domain of Grb2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13094)
6. [Cooperative interactions at the SLP‐76 complex are critical for actin polymerization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13094)
7. [Functional Association between SLAP-130 and SLP-76 in Jurkat T Cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13094)
8. [Vav and SLP-76 Interact and Functionally Cooperate in IL-2 Gene Activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13094)
9. [Efficient T‐cell receptor signaling requires a high‐affinity interaction between the Gads C‐SH3 domain and the SLP‐76 RxxK motif](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13094)
10. [Cutting edge: SLP-76 cooperativity with FYB/FYN-T in the Up-regulation of TCR-driven IL-2 transcription requires SLP-76 binding to FYB at Tyr595 and Tyr651](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13094)
11. [The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13094)
12. [Towards a proteome-scale map of the human protein–protein interaction network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13094)
13. [A human MAP kinase interactome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13094)
14. [Association of Nck with tyrosine-phosphorylated SLP-76 in activated T lymphocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13094)
15. [SLP-76 and Vav Function in Separate, but Overlapping Pathways to Augment Interleukin-2 Promoter Activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13094)
16. [The kinase GLK controls autoimmunity and NF-κB signaling by activating the kinase PKC-θ in T cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13094)
17. [Phospho‐tyrosine dependent protein–protein interaction network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13094)
18. [Expression, refolding and crystallizations of the Grb2-like (GADS) C-terminal SH3 domain complexed with a SLP-76 motif peptide](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13094)
19. [SH2 domain containing leukocyte phosphoprotein of 76-kDa (SLP-76) feedback regulation of ZAP-70 microclustering](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13094)
20. [Sequential phosphorylation of SLP‐76 at tyrosine 173 is required for activation of T and mast cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13094)
21. [Charting the molecular network of the drug target Bcr-Abl](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13094)
22. [Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13094)
23. [LuTHy: a double‐readout bioluminescence‐based two‐hybrid technology for quantitative mapping of protein–protein interactions in mammalian cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13094)
24. [Improved Two-Dimensional Reversed Phase-Reversed Phase LC-MS/MS Approach for Identification of Peptide-Protein Interactions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13094)
25. [Recruitment and activation of PLCγ1 in T cells: a new insight into old domains](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13094)
26. [Next-generation sequencing to generate interactome datasets](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13094)
27. [A Proteome-Scale Map of the Human Interactome Network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13094)
28. [Quantitative proteomics analysis of signalosome dynamics in primary T cells identifies the surface receptor CD6 as a Lat adaptor–independent TCR signaling hub](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13094)
29. [SLP-76 mediates and maintains activation of the Tec family kinase ITK via the T cell antigen receptor-induced association between SLP-76 and ITK](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13094)
30. [Regulation of Vav–SLP-76 Binding by ZAP-70 and Its Relevance to TCRζ/CD3 Induction of Interleukin-2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13094)
31. [Crystal structure of the C-terminal SH3 domain of the adaptor protein GADS in complex with SLP-76 motif peptide reveals a unique SH3–SH3 interaction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13094)
32. [Novel Src Homology 3 Domain-binding Motifs Identified from Proteomic Screen of a Pro-rich Region](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13094)
33. [Pooled‐matrix protein interaction screens using Barcode Fusion Genetics](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13094)
34. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13094)
35. [Ezrin tunes T‐cell activation by controlling Dlg1 and microtubule positioning at the immunological synapse](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13094)
36. [T Cell Receptor-Independent Basal Signaling via Erk and Abl Kinases Suppresses RAG Gene Expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13094)
37. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13094)
38. [Molecular Cloning of SLP-76, a 76-kDa Tyrosine Phosphoprotein Associated with Grb2 in T Cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13094)
39. [Molecular Cloning of SLP-76, a 76-kDa Tyrosine Phosphoprotein Associated with Grb2 in T Cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13094&geneProductId=UniProtKB:Q13094)
40. Ensembl Release 99
41. [Identifiers.org](https://registry.identifiers.org/registry/uniprot)