# Low density lipoprotein receptor-related protein 1

> mammalian protein found in Mus musculus

**Wikidata**: [Q21981326](https://www.wikidata.org/wiki/Q21981326)  
**Source**: https://4ort.xyz/entity/low-density-lipoprotein-receptor-related-protein-1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q91ZX7)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZX7)
5. [Surface location and high affinity for calcium of a 500-kd liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZX7)
6. [LDL receptor-related protein as a component of the midkine receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZX7)
7. [Amyloid precursor protein regulates brain apolipoprotein E and cholesterol metabolism through lipoprotein receptor LRP1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZX7)
8. [Interaction of the apolipoprotein E receptors low density lipoprotein receptor-related protein and sorLA/LR11](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZX7)
9. [Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZX7)
10. [Lipoprotein receptor LRP1 regulates leptin signaling and energy homeostasis in the adult central nervous system](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZX7)
11. [Targeted tandem affinity purification of PSD-95 recovers core postsynaptic complexes and schizophrenia susceptibility proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZX7)
12. [Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZX7)
13. [Characterization of the adaptor protein ARH expression in the brain and ARH molecular interactions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZX7)
14. [Extensive proteomic screening identifies the obesity-related NYGGF4 protein as a novel LRP1-interactor, showing reduced expression in early Alzheimer's disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZX7)
15. [Heparan Sulphate Proteoglycan and the Low-Density Lipoprotein Receptor-Related Protein 1 Constitute Major Pathways for Neuronal Amyloid-β Uptake](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q91ZX7&geneProductId=UniProtKB:Q91ZX7)
16. [Heparan Sulphate Proteoglycan and the Low-Density Lipoprotein Receptor-Related Protein 1 Constitute Major Pathways for Neuronal Amyloid-β Uptake](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZX7)
17. [Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZX7)
18. [Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZX7)
19. [LRP1 regulates architecture of the vascular wall by controlling PDGFRbeta-dependent phosphatidylinositol 3-kinase activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZX7)
20. [Global genetic analysis in mice unveils central role for cilia in congenital heart disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZX7)
21. [LRP1 controls cPLA2 phosphorylation, ABCA1 expression and cellular cholesterol export](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZX7)
22. [Abnormal development of the apical ectodermal ridge and polysyndactyly in Megf7-deficient mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZX7)
23. [Epithelial cells as phagocytes: apoptotic epithelial cells are engulfed by mammary alveolar epithelial cells and repress inflammatory mediator release](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZX7)
24. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q91ZX7&geneProductId=UniProtKB:Q91ZX7)
25. [LRAD3, A Novel Low-Density Lipoprotein Receptor Family Member That Modulates Amyloid Precursor Protein Trafficking](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q91ZX7&geneProductId=UniProtKB:Q91ZX7)
26. [SRF and myocardin regulate LRP-mediated amyloid-beta clearance in brain vascular cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q91ZX7&geneProductId=UniProtKB:Q91ZX7)
27. [LRP1 in Brain Vascular Smooth Muscle Cells Mediates Local Clearance of Alzheimer's Amyloid-β](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZX7)
28. [Neuronal Clearance of Amyloid-β by Endocytic Receptor LRP1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZX7)
29. [LRAD3, A Novel Low-Density Lipoprotein Receptor Family Member That Modulates Amyloid Precursor Protein Trafficking](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZX7)
30. [LRP1 in Brain Vascular Smooth Muscle Cells Mediates Local Clearance of Alzheimer's Amyloid-β](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q91ZX7&geneProductId=UniProtKB:Q91ZX7)
31. [Neuronal Clearance of Amyloid-β by Endocytic Receptor LRP1](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q91ZX7&geneProductId=UniProtKB:Q91ZX7)
32. [Prosaposin facilitates sortilin-independent lysosomal trafficking of progranulin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZX7)
33. [SRF and myocardin regulate LRP-mediated amyloid-beta clearance in brain vascular cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZX7)
34. ensembl Release 106