# Lareb

> drug and vaccine research facility in 's-Hertogenbosch, Netherlands

**Wikidata**: [Q2659475](https://www.wikidata.org/wiki/Q2659475)  
**Source**: https://4ort.xyz/entity/lareb

## Summary
Lareb is a drug and vaccine research facility based in 's-Hertogenbosch, Netherlands. It operates as the Netherlands Pharmacovigilance Centre and maintains the National Register for the Evaluation of Side Effects. Its primary focus is monitoring and researching adverse effects related to medications and vaccines.

## Key Facts
- Official name: Netherlands Pharmacovigilance Centre Lareb
- Aliases: Lareb, National Register for Evaluation of Side Effects
- Location: 's-Hertogenbosch, Netherlands
- Instance of: Research institute
- GRID ID: grid.419940.1
- ROR ID: 04fp8ns78
- ISNI: 0000000406319549
- Ringgold ID: 61371
- Website: [http://www.lareb.nl/](http://www.lareb.nl/)
- Wikidata description: Drug and vaccine research facility in 's-Hertogenbosch, Netherlands
- Google Knowledge Graph ID: /g/122jr79f
- Wikipedia languages: German (de), Dutch (nl)

## FAQs
### Q: What does Lareb do?
A: Lareb monitors and evaluates side effects of drugs and vaccines in the Netherlands. It collects reports of adverse reactions and conducts research to improve medication safety.

### Q: Where is Lareb located?
A: Lareb is located in 's-Hertogenbosch, a city in the southern part of the Netherlands.

### Q: Is Lareb a government agency?
A: Lareb functions as an independent research institute focused on pharmacovigilance. It collaborates with regulatory bodies but is not a direct arm of the government.

## Why It Matters
Lareb plays a critical role in public health by ensuring the safe use of medicines and vaccines in the Netherlands. As the national pharmacovigilance center, it identifies, analyzes, and communicates risks associated with pharmaceutical products. By maintaining a registry of adverse effects and conducting post-market surveillance, Lareb contributes to informed decision-making by healthcare professionals and regulatory agencies. Its work helps prevent harm, supports safer prescribing practices, and enhances trust in medical treatments. The institute also participates in international collaborations, contributing to global efforts in drug safety monitoring.

## Notable For
- Serving as the official Netherlands Pharmacovigilance Centre
- Operating the National Register for the Evaluation of Side Effects
- Maintaining internationally recognized identifiers (ISNI, ROR, GRID, Ringgold)
- Hosting a dedicated research infrastructure for post-market drug and vaccine safety
- Providing publicly accessible information and resources through its website

## Body
### Overview
Lareb, formally known as the Netherlands Pharmacovigilance Centre, is a specialized research institute located in 's-Hertogenbosch, Netherlands. It focuses on the study and monitoring of adverse effects caused by drugs and vaccines used within the country.

### Functions and Responsibilities
- Collects and evaluates reports of suspected adverse drug reactions (ADRs) and adverse events following immunization (AEFIs).
- Operates the National Register for the Evaluation of Side Effects, which serves as a central database for reported cases.
- Conducts signal detection and safety studies to identify potential risks associated with pharmaceutical products.
- Collaborates with healthcare providers, patients, and regulatory authorities such as the Dutch Medicines Evaluation Board (MEB).
- Engages in educational outreach and public awareness initiatives regarding medication safety.

### Institutional Identity
- Recognized under multiple international identification systems including:
  - ISNI: 0000000406319549
  - ROR ID: 04fp8ns78
  - GRID ID: grid.419940.1
  - Ringgold ID: 61371
- Listed in Wikidata with the description: “drug and vaccine research facility in 's-Hertogenbosch, Netherlands”
- Has site links in German and Dutch Wikipedias, indicating cross-language recognition

### Online Presence
- Official website: [http://www.lareb.nl/](http://www.lareb.nl/)
- Provides access to databases, annual reports, newsletters, and educational materials
- Offers tools for reporting side effects directly from patients and healthcare professionals

### Geographic and Administrative Context
- Located in 's-Hertogenbosch (Den Bosch), North Brabant province
- Functions independently while aligning with European and global pharmacovigilance standards
- Works closely with EMA (European Medicines Agency) and WHO’s Uppsala Monitoring Centre for international data sharing and benchmarking

## References

1. Aligned ISNI and Ringgold identifiers for institutions