# Kruppel like factor 4

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21114206](https://www.wikidata.org/wiki/Q21114206)  
**Source**: https://4ort.xyz/entity/kruppel-like-factor-4


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O43474)
3. Q20641742
4. [Swiss-Prot](http://www.uniprot.org/uniprot/Q60793.txt?version=142)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43474)
6. [Klf4 is a transcription factor required for establishing the barrier function of the skin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43474)
7. [Human EZF, a Krüppel-like zinc finger protein, is expressed in vascular endothelial cells and contains transcriptional activation and repression domains](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43474)
8. [Krüppel-like Factor 4 activates HBG gene expression in primary erythroid cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=O43474&geneProductId=UniProtKB:O43474)
9. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O43474&geneProductId=UniProtKB:O43474)
10. [Krüppel-like Factor 4 activates HBG gene expression in primary erythroid cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43474)
11. [C-terminal binding proteins (CtBPs) attenuate KLF4-mediated transcriptional activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43474)
12. [Deterministic direct reprogramming of somatic cells to pluripotency](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43474)
13. [Forkhead Box C1 Regulates Human Primary Keratinocyte Terminal Differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43474)
14. [A census of human transcription factors: function, expression and evolution](http://www.ebi.ac.uk/QuickGO/annotations?protein=O43474&geneProductId=UniProtKB:O43474)
15. [A census of human transcription factors: function, expression and evolution](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43474)
16. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43474)
17. [Erk5 activation elicits a vasoprotective endothelial phenotype via induction of Kruppel-like factor 4 (KLF4)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43474)
18. [A regulatory role of Kruppel-like factor 4 in endothelial argininosuccinate synthetase 1 expression in response to laminar shear stress](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43474)
19. [Site-Specific MicroRNA-92a Regulation of Krüppel-Like Factors 4 and 2 in Atherosusceptible Endothelium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43474)
20. [Krüppel-like transcription factor 4 contributes to maintenance of telomerase activity in stem cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43474)
21. [A gene for a novel zinc-finger protein expressed in differentiated epithelial cells and transiently in certain mesenchymal cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43474)
22. [Wnt/β-catenin signaling regulates telomerase in stem cells and cancer cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43474)
23. [Identification and characterization of a gene encoding a gut-enriched Krüppel-like factor expressed during growth arrest](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43474)
24. [Key role of microRNA-15a in the KLF4 suppressions of proliferation and angiogenesis in endothelial and vascular smooth muscle cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43474)
25. [Inhibition of miR-7 promotes angiogenesis in human umbilical vein endothelial cells by upregulating VEGF via KLF4.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43474)
26. Ensembl Release 99
27. UMLS 2023