# Kruppel like factor 4

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q29523618](https://www.wikidata.org/wiki/Q29523618)  
**Source**: https://4ort.xyz/entity/kruppel-like-factor-4-q29523618


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q923V7)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q923V7)
5. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q923V7)
6. [ATRA activates and PDGF-BB represses the SM22α promoter through KLF4 binding to, or dissociating from, its cis-DNA elements](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q923V7)
7. [Induction of p53 by GKLF is essential for inhibition of proliferation of vascular smooth muscle cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q923V7)
8. [Synergistic activation of the rat laminin gamma1 chain promoter by the gut-enriched Kruppel-like factor (GKLF/KLF4) and Sp1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q923V7)
9. [Krüppel-like factor 4 inhibits proliferation by platelet-derived growth factor receptor beta-mediated, not by retinoic acid receptor alpha-mediated, phosphatidylinositol 3-kinase and ERK signaling in vascular smooth muscle cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q923V7)
10. [All-trans retinoic acid increases KLF4 acetylation by inducing HDAC2 phosphorylation and its dissociation from KLF4 in vascular smooth muscle cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q923V7)
11. [Combinatorial control of the bradykinin B2 receptor promoter by p53, CREB, KLF-4, and CBP: implications for terminal nephron differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q923V7)
12. [Differential regulation of Krüppel-like factor family transcription factor expression in neonatal rat cardiac myocytes: effects of endothelin-1, oxidative stress and cytokines](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q923V7)