# Kruppel-like factor 4 (gut)

> mammalian protein found in Mus musculus

**Wikidata**: [Q21983400](https://www.wikidata.org/wiki/Q21983400)  
**Source**: https://4ort.xyz/entity/kruppel-like-factor-4-gut-


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q60793)
3. Q20641742
4. [Mammalian SP/KLF transcription factors: bring in the family](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60793)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60793)
6. [Wnt/β-catenin signaling regulates telomerase in stem cells and cancer cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60793)
7. [Wnt/β-catenin signaling regulates telomerase in stem cells and cancer cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60793&geneProductId=UniProtKB:Q60793)
8. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60793&geneProductId=UniProtKB:Q60793)
9. [DLK2 Is a Transcriptional Target of KLF4 in the Early Stages of Adipogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60793&geneProductId=UniProtKB:Q60793)
10. [DLK2 Is a Transcriptional Target of KLF4 in the Early Stages of Adipogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60793)
11. [Klf4 interacts directly with Oct4 and Sox2 to promote reprogramming](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60793)
12. [Transcriptional regulation of adipogenesis by KLF4](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60793)
13. [Combined Overexpression of JARID2, PRDM14, ESRRB, and SALL4A Dramatically Improves Efficiency and Kinetics of Reprogramming to Induced Pluripotent Stem Cells.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60793)
14. [ERK1 and ERK2 regulate embryonic stem cell self-renewal through phosphorylation of Klf4.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60793)
15. [Klf4 and corticosteroids activate an overlapping set of transcriptional targets to accelerate in utero epidermal barrier acquisition](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60793)
16. [A gene for a novel zinc-finger protein expressed in differentiated epithelial cells and transiently in certain mesenchymal cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60793)
17. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60793)
18. [Cross-talk between KLF4 and STAT3 regulates axon regeneration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60793)
19. [Human EZF, a Krüppel-like zinc finger protein, is expressed in vascular endothelial cells and contains transcriptional activation and repression domains](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60793&geneProductId=UniProtKB:Q60793)
20. [Cross-talk between KLF4 and STAT3 regulates axon regeneration](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60793&geneProductId=UniProtKB:Q60793)
21. [Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60793&geneProductId=UniProtKB:Q60793)
22. [Zfp296 is a novel Klf4-interacting protein and functions as a negative regulator](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60793&geneProductId=UniProtKB:Q60793)
23. [Human EZF, a Krüppel-like zinc finger protein, is expressed in vascular endothelial cells and contains transcriptional activation and repression domains](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60793)
24. [Zfp296 is a novel Klf4-interacting protein and functions as a negative regulator](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60793)
25. [Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60793)
26. [Klf4 is a transcription factor required for establishing the barrier function of the skin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60793)
27. [Conditional deletion of the mouse Klf4 gene results in corneal epithelial fragility, stromal edema, and loss of conjunctival goblet cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60793)
28. [Detailed characterization of the mouse embryonic stem cell transcriptome reveals novel genes and intergenic splicing associated with pluripotency](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60793)
29. [Transcription factor Klf4, induced in the lung by oxygen at birth, regulates perinatal fibroblast and myofibroblast differentiation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q60793&geneProductId=UniProtKB:Q60793)
30. [Murine embryonic stem cell differentiation is promoted by SOCS-3 and inhibited by the zinc finger transcription factor Klf4](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60793)
31. [Deficiency of the Kruppel-like factor KLF4 correlates with increased cell proliferation and enhanced skin tumorigenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60793)
32. [Haploinsufficiency of Krüppel-like factor 4 promotes adenomatous polyposis coli dependent intestinal tumorigenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60793)
33. [Identification and characterization of a gene encoding a gut-enriched Krüppel-like factor expressed during growth arrest](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60793)
34. [miRNA 34a, 100, and 137 modulate differentiation of mouse embryonic stem cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60793)
35. [Klf4 cooperates with Oct3/4 and Sox2 to activate the Lefty1 core promoter in embryonic stem cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60793)
36. [Transcription factor Klf4, induced in the lung by oxygen at birth, regulates perinatal fibroblast and myofibroblast differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q60793)
37. ensembl Release 106