# Kruppel like factor 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21173394](https://www.wikidata.org/wiki/Q21173394)  
**Source**: https://4ort.xyz/entity/kruppel-like-factor-1-q21173394


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q13351)
3. Q20641742
4. [Isolation, genomic structure, and expression of human erythroid Krüppel-like factor (EKLF)](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13351&geneProductId=UniProtKB:Q13351)
5. [A SWI/SNF-related chromatin remodeling complex, E-RC1, is required for tissue-specific transcriptional regulation by EKLF in vitro](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13351&geneProductId=UniProtKB:Q13351)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13351)
7. [Krüppel-like Factor 4 activates HBG gene expression in primary erythroid cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13351&geneProductId=UniProtKB:Q13351)
8. [Structural and functional characterization of an atypical activation domain in erythroid Kruppel-like factor (EKLF)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13351)
9. [A census of human transcription factors: function, expression and evolution](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13351&geneProductId=UniProtKB:Q13351)
10. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13351&geneProductId=UniProtKB:Q13351)
11. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13351)
12. [A census of human transcription factors: function, expression and evolution](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13351)
13. [Krüppel-like Factor 4 activates HBG gene expression in primary erythroid cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13351)
14. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13351&geneProductId=UniProtKB:Q13351)
15. [Isolation, genomic structure, and expression of human erythroid Krüppel-like factor (EKLF)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13351)
16. [A SWI/SNF-related chromatin remodeling complex, E-RC1, is required for tissue-specific transcriptional regulation by EKLF in vitro](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13351)
17. [Compound heterozygosity for KLF1 mutations is associated with microcytic hypochromic anemia and increased fetal hemoglobin](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13351&geneProductId=UniProtKB:Q13351)
18. [A dominant mutation in the gene encoding the erythroid transcription factor KLF1 causes a congenital dyserythropoietic anemia](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13351&geneProductId=UniProtKB:Q13351)
19. [A dominant mutation in the gene encoding the erythroid transcription factor KLF1 causes a congenital dyserythropoietic anemia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13351)
20. [Compound heterozygosity for KLF1 mutations is associated with microcytic hypochromic anemia and increased fetal hemoglobin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13351)
21. [The role of p22 NF-E4 in human globin gene switching](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13351)
22. [Haploinsufficiency for the erythroid transcription factor KLF1 causes hereditary persistence of fetal hemoglobin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13351)
23. Ensembl Release 99