# Karyopherin subunit alpha 2

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21131854](https://www.wikidata.org/wiki/Q21131854)  
**Source**: https://4ort.xyz/entity/karyopherin-subunit-alpha-2-q21131854


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P52292)
3. Q20641742
4. [Regulation of histone deacetylase 4 and 5 and transcriptional activity by 14-3-3-dependent cellular localization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52292)
5. [Structural basis for regulation of the nucleo-cytoplasmic distribution of Bag6 by TRC35.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52292)
6. [ARL4, an ARF-like protein that is developmentally regulated and localized to nuclei and nucleoli](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52292)
7. [Specificity of Hexim1 and Hexim2 complex formation with cyclin T1/T2, importin alpha and 7SK snRNA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52292)
8. [Analysis of nuclear transport signals in the human apurinic/apyrimidinic endonuclease (APE1/Ref1).](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52292)
9. [The second AT-hook of the architectural transcription factor HMGA2 is determinant for nuclear localization and function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52292)
10. [CTNNBL1 is a novel nuclear localization sequence-binding protein that recognizes RNA-splicing factors CDC5L and Prp31](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52292)
11. [Karyopherin alpha7 (KPNA7), a divergent member of the importin alpha family of nuclear import receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52292)
12. [Interactions between HIV rev and nuclear import and export factors: the rev nuclear localisation signal mediates specific binding to human importin-β](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52292)
13. [Identification of two novel RanGTP-binding proteins belonging to the importin beta superfamily](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52292)
14. [Cloning of a cDNA encoding a novel importin-alpha homologue, Qip1: discrimination of Qip1 and Rch1 from hSrp1 by their ability to interact with DNA helicase Q1/RecQL](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52292)
15. [Nuclear import strategies of high risk HPV16 L1 major capsid protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52292)
16. [The l2 minor capsid protein of human papillomavirus type 16 interacts with a network of nuclear import receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52292)
17. [Evidence for distinct substrate specificities of importin alpha family members in nuclear protein import](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52292)
18. [A human interactome in three quantitative dimensions organized by stoichiometries and abundances](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52292)
19. [Mammalian splicing factor SF1 interacts with SURP domains of U2 snRNP-associated proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52292)
20. [Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52292)
21. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52292)
22. [Structure of importin-beta bound to the IBB domain of importin-alpha](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52292)
23. [The molecular basis for the regulation of the cap-binding complex by the importins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52292)
24. [Regulation of nuclear localization signal‐importin α interaction by Ca2+/S100A6](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52292)
25. [Identification of a Novel Cytoplasmic Protein That Specifically Binds to Nuclear Localization Signal Motifs](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52292)
26. [Toward an understanding of the protein interaction network of the human liver](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52292)
27. [A classical NLS and the SUN domain contribute to the targeting of SUN2 to the inner nuclear membrane](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52292)
28. [Nuclear entry of high-risk human papillomavirus type 16 E6 oncoprotein occurs via several pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52292)
29. [The nuclear import of TAF10 is regulated by one of its three histone fold domain-containing interaction partners](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52292)
30. [Host factors that interact with the pestivirus N-terminal protease, Npro, are components of the ribonucleoprotein complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52292)
31. [New host factors important for respiratory syncytial virus (RSV) replication revealed by a novel microfluidics screen for interactors of matrix (M) protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52292)
32. [The mRNA-Bound Proteome and Its Global Occupancy Profile on Protein-Coding Transcripts](http://www.ebi.ac.uk/QuickGO/annotations?protein=P52292&geneProductId=UniProtKB:P52292)
33. [The mRNA-Bound Proteome and Its Global Occupancy Profile on Protein-Coding Transcripts](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52292)
34. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52292)
35. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P52292&geneProductId=UniProtKB:P52292)
36. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P52292&geneProductId=UniProtKB:P52292)
37. [Identification of hSRP1 alpha as a functional receptor for nuclear localization sequences](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52292)
38. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52292)
39. [Synapse to nucleus signaling during long-term synaptic plasticity; a role for the classical active nuclear import pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52292)
40. [Rch1, a protein that specifically interacts with the RAG-1 recombination-activating protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52292)
41. [H7N9 Influenza A Virus Exhibits Importin-α7-Mediated Replication in the Mammalian Respiratory Tract](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52292)
42. Ensembl Release 99
43. Transporter Classification database