# Jagged canonical Notch ligand 1

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28561047](https://www.wikidata.org/wiki/Q28561047)  
**Source**: https://4ort.xyz/entity/jagged-canonical-notch-ligand-1-q28561047


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q63722)
3. Q20641742
4. [Jagged: A mammalian ligand that activates notch1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63722)
5. [Deciphering the Fringe-Mediated Notch Code: Identification of Activating and Inhibiting Sites Allowing Discrimination between Ligands](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63722)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63722)
7. [Aph-1 associates directly with full-length and C-terminal fragments of gamma-secretase substrates](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63722)
8. [Low density lipoprotein receptor-related protein-1 (LRP1) regulates thrombospondin-2 (TSP2) enhancement of Notch3 signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63722)
9. [Expression of Notch-1 and its ligand Jagged-1 in rat liver during liver regeneration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63722)
10. [Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63722)
11. [Identification and Cloning of the Human Homolog (JAG1) of the RatJagged1Gene from the Alagille Syndrome Critical Region at 20p12](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63722)
12. [NOTCH1 missense alleles associated with left ventricular outflow tract defects exhibit impaired receptor processing and defective EMT.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63722)
13. [Members of the Jagged/Notch gene families are expressed in injured arteries and regulate cell phenotype via alterations in cell matrix and cell-cell interaction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63722)
14. [Notch signaling regulates the pattern of auditory hair cell differentiation in mammals](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63722)
15. [NOTCH1 mutations in individuals with left ventricular outflow tract malformations reduce ligand-induced signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63722)
16. ensembl Release 106