# Jagged 1

> mammalian protein found in Mus musculus

**Wikidata**: [Q21985075](https://www.wikidata.org/wiki/Q21985075)  
**Source**: https://4ort.xyz/entity/jagged-1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q9QXX0)
3. Q20641742
4. [Mouse jagged1 physically interacts with notch2 and other notch receptors. Assessment by quantitative methods](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXX0)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXX0)
6. [Binding of Delta1, Jagged1, and Jagged2 to Notch2 rapidly induces cleavage, nuclear translocation, and hyperphosphorylation of Notch2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXX0)
7. [The extracellular matrix protein MAGP-2 interacts with Jagged1 and induces its shedding from the cell surface](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXX0)
8. [Fringe glycosyltransferases differentially modulate Notch1 proteolysis induced by Delta1 and Jagged1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXX0)
9. [Mind bomb 1 is essential for generating functional Notch ligands to activate Notch](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXX0)
10. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXX0)
11. [Cadherin-based adhesions in the apical endfoot are required for active Notch signaling to control neurogenesis in vertebrates](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXX0)
12. [Notch ligands with contrasting functions: Jagged1 and Delta1 in the mouse inner ear](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXX0)
13. [Segmental expression of Notch and Hairy genes in nephrogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXX0)
14. [RBPJ in mouse Sertoli cells is required for proper regulation of the testis stem cell niche](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXX0)
15. [Notch4 reveals a novel mechanism regulating Notch signal transduction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXX0)
16. [Hepatic Notch2 deficiency leads to bile duct agenesis perinatally and secondary bile duct formation after weaning](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXX0)
17. [Stroma-mediated dysregulation of myelopoiesis in mice lacking I kappa B alpha](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXX0)
18. [Dual roles for the Notch target gene Hes-1 in the differentiation of 3T3-L1 preadipocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXX0)
19. [The extracellular domain of Notch2 increases its cell-surface abundance and ligand responsiveness during kidney development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXX0)
20. [Murine Jagged1/Notch signaling in the second heart field orchestrates Fgf8 expression and tissue-tissue interactions during outflow tract development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXX0)
21. [Domain-specific control of neurogenesis achieved through patterned regulation of Notch ligand expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXX0)
22. [Intracellular Pathogen Sensor NOD2 Programs Macrophages to Trigger Notch1 Activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXX0)
23. [Notch2 regulates BMP signaling and epithelial morphogenesis in the ciliary body of the mouse eye](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXX0)
24. [Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXX0)
25. [Strawberry notch homologue 2 regulates osteoclast fusion by enhancing the expression of DC-STAMP](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXX0)
26. [The mouse slalom mutant demonstrates a role for Jagged1 in neuroepithelial patterning in the organ of Corti](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXX0)
27. [Catweasel mice: a novel role for Six1 in sensory patch development and a model for branchio-oto-renal syndrome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXX0)
28. [A mouse model of Alagille syndrome: Notch2 as a genetic modifier of Jag1 haploinsufficiency](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXX0)
29. [MicroRNA-199b Modulates Vascular Cell Fate During iPS Cell Differentiation by Targeting the Notch Ligand Jagged1 and Enhancing VEGF Signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXX0)
30. [Functional diversity of notch family genes in fetal lung development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QXX0)
31. ensembl Release 106