# ISL LIM homeobox 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21114762](https://www.wikidata.org/wiki/Q21114762)  
**Source**: https://4ort.xyz/entity/isl-lim-homeobox-1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P61371)
3. Q20641742
4. [Swiss-Prot](http://www.uniprot.org/uniprot/P61372.txt?version=115)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61371)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61371&geneProductId=UniProtKB:P61371)
7. [The LIM-homeodomain protein ISL1 activates insulin gene promoter directly through synergy with BETA2](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61371&geneProductId=UniProtKB:P61371)
8. [ISL1 physically interacts with BETA2 to promote insulin gene transcriptional synergy in non-beta cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61371)
9. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61371)
10. [Characterization of the LIM/homeodomain gene islet-1 and single nucleotide screening in NIDDM](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61371)
11. [The LIM-homeodomain protein ISL1 activates insulin gene promoter directly through synergy with BETA2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61371)
12. [A census of human transcription factors: function, expression and evolution](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61371&geneProductId=UniProtKB:P61371)
13. [A census of human transcription factors: function, expression and evolution](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61371)
14. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61371)
15. [The LIM domain homeobox gene isl-1: conservation of human, hamster, and rat complementary deoxyribonucleic acid sequences and expression in cell types of nonneuroendocrine lineage](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61371)
16. [The LIM domain homeobox gene isl-1: conservation of human, hamster, and rat complementary deoxyribonucleic acid sequences and expression in cell types of nonneuroendocrine lineage](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61371&geneProductId=UniProtKB:P61371)
17. [Human ISL1 heart progenitors generate diverse multipotent cardiovascular cell lineages](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61371)
18. [Common variation in ISL1 confers genetic susceptibility for human congenital heart disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61371)
19. [RIT2, a neuron-specific small guanosine triphosphatase, is expressed in retinal neuronal cells and its promoter is modulated by the POU4 transcription factors](http://www.ebi.ac.uk/QuickGO/annotations?protein=P61371&geneProductId=UniProtKB:P61371)
20. [RIT2, a neuron-specific small guanosine triphosphatase, is expressed in retinal neuronal cells and its promoter is modulated by the POU4 transcription factors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61371)
21. Ensembl Release 99