# ISG15 ubiquitin like modifier

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21101451](https://www.wikidata.org/wiki/Q21101451)  
**Source**: https://4ort.xyz/entity/isg15-ubiquitin-like-modifier


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P05161)
3. Q20641742
4. [ISG15 inhibits Ebola VP40 VLP budding in an L-domain-dependent manner by blocking Nedd4 ligase activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05161)
5. [Structural basis for the sequence-specific recognition of human ISG15 by the NS1 protein of influenza B virus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05161)
6. [Dual E1 activation systems for ubiquitin differentially regulate E2 enzyme charging](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05161)
7. [Molecular basis for ubiquitin and ISG15 cross-reactivity in viral ovarian tumor domains](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05161)
8. [Towards a proteome-scale map of the human protein–protein interaction network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05161)
9. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05161)
10. [Negative regulation of protein phosphatase 2Cbeta by ISG15 conjugation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05161)
11. [ISG15 modification of filamin B negatively regulates the type I interferon-induced JNK signalling pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05161)
12. [Structural basis for the removal of ubiquitin and interferon-stimulated gene 15 by a viral ovarian tumor domain-containing protease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05161)
13. [Human intracellular ISG15 prevents interferon-α/β over-amplification and auto-inflammation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05161)
14. [ISG15 conjugation system targets the viral NS1 protein in influenza A virus-infected cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05161)
15. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05161)
16. [Extracellular ISG15 Signals Cytokine Secretion through the LFA-1 Integrin Receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05161)
17. [Mycobacterial disease and impaired IFN-γ immunity in humans with inherited ISG15 deficiency](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05161)
18. [Interferon-induced ISG15 conjugation inhibits influenza A virus gene expression and replication in human cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05161)
19. [Mechanism of Inhibition of Retrovirus Release from Cells by Interferon-Induced Gene ISG15](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05161)
20. [ISG15 modification of ubiquitin E2 Ubc13 disrupts its ability to form thioester bond with ubiquitin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05161)
21. Ensembl Release 99
22. [Identifiers.org](https://registry.identifiers.org/registry/uniprot)