# irreversible antagonist

> type of antagonist that binds permanently to a receptor, either by forming a covalent bond to the active site, or alternatively just by binding so tightly that the rate of dissociation is effectively zero at relevant time scales

**Wikidata**: [Q6073768](https://www.wikidata.org/wiki/Q6073768)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/Irreversible_antagonist)  
**Source**: https://4ort.xyz/entity/irreversible-antagonist