# Interleukin 4

> mammalian protein found in Mus musculus

**Wikidata**: [Q14865947](https://www.wikidata.org/wiki/Q14865947)  
**Source**: https://4ort.xyz/entity/interleukin-4-q14865947


## References

1. UniProt
2. Online Mendelian Inheritance in Man
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P07750)
4. Q20641742
5. ensembl Release 106
6. [The anti-apoptotic molecules Bcl-xL and Bcl-w target protein phosphatase 1alpha to Bad](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750)
7. [T-bet regulates T-independent IgG2a class switching](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750)
8. [Involvement of the Jak-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750)
9. [Expressed genes in interleukin-4 treated Bcellsidentified by cDNA representational differenceanalysis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750)
10. [Differential requirements of CD45 for lymphocyte development and function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750)
11. [Protein phosphatase subunit G5PR is needed for inhibition of B cell receptor-induced apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750)
12. [Impaired IgA class switching in APRIL-deficient mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750)
13. [IL-4 inhibits TGF-beta-induced Foxp3+ T cells and, together with TGF-beta, generates IL-9+ IL-10+ Foxp3(-) effector T cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750)
14. [Enforced expression of GATA3 allows differentiation of IL-17-producing cells, but constrains Th17-mediated pathology](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750)
15. [Control of inflammation, cytokine expression, and germinal center formation by BCL-6](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750)
16. [M17, a gene specific for germinal center (GC) B cells and a prognostic marker for GC B-cell lymphomas, is dispensable for the GC reaction in mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750)
17. [Interleukin 4 increases type 5 acid phosphatase mRNA expression in murine bone marrow macrophages](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750)
18. [IL-4 induces IL-2 receptor p75 beta-chain gene expression and IL-2-dependent proliferation in mouse T lymphocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750)
19. [Enhancer-mediated control of macrophage-specific arginase I expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750)
20. [Stat5 activation is uniquely associated with cytokine signaling in peripheral T cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750)
21. [Stat5b is essential for natural killer cell-mediated proliferation and cytolytic activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750)
22. [Recombinant soluble interleukin-4 (IL-4) receptor acts as an antagonist of IL-4 in murine cutaneous Leishmaniasis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750)
23. [Stat5 activation is uniquely associated with cytokine signaling in peripheral T cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P07750&geneProductId=UniProtKB:P07750)
24. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750)
25. [TCR-dependent translational control of GATA-3 enhances Th2 differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750)
26. [Cross-linking of OX40 ligand, a member of the TNF/NGF cytokine family, induces proliferation and differentiation in murine splenic B cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750)
27. [RUN and FYVE domain-containing protein 4 enhances autophagy and lysosome tethering in response to Interleukin-4.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750)
28. [IL-4-induced selective clearance of oligomeric beta-amyloid peptide(1-42) by rat primary type 2 microglia.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P07750&geneProductId=UniProtKB:P07750)
29. [Eosinophils and type 2 cytokine signaling in macrophages orchestrate development of functional beige fat.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750)
30. [IL-4-induced selective clearance of oligomeric beta-amyloid peptide(1-42) by rat primary type 2 microglia.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750)
31. [Inflammatory microglia are glycolytic and iron retentive and typify the microglia in APP/PS1 mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07750)
32. HomoloGene build68
33. [Identifiers.org](http://www.ebi.ac.uk/miriam/main/collections/MIR:00000069)
34. [Bgee](https://bgee.org/bgee15_0/gene/ENSG00000113520)
35. National Library of Israel Names and Subjects Authority File
36. [OpenAlex](https://docs.openalex.org/download-snapshot/snapshot-data-format)