# Interleukin 2

> mammalian protein found in Homo sapiens

**Wikidata**: [Q410130](https://www.wikidata.org/wiki/Q410130)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/Interleukin_2)  
**Source**: https://4ort.xyz/entity/interleukin-2


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P60568)
3. Nuovo soggettario
4. Q20641742
5. Freebase Data Dumps. 2013
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60568)
7. [Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60568)
8. [Development and function of T cells in mice rendered interleukin-2 deficient by gene targeting](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60568)
9. [Similarities between interleukin-2 receptor number and affinity on activated B and T lymphocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60568)
10. [Definition and spatial location of mouse interleukin-2 residues that interact with its heterotrimeric receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60568)
11. [The IL-2 receptor complex: its structure, function, and target genes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60568)
12. [Exploiting a natural conformational switch to engineer an interleukin-2 'superkine'](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60568)
13. [Crystal structure of the IL-2 signaling complex: paradigm for a heterotrimeric cytokine receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60568)
14. [Hot-spot mimicry of a cytokine receptor by a small molecule](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60568)
15. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P60568&geneProductId=UniProtKB:P60568)
16. [T-cell growth factor: complete nucleotide sequence and organization of the gene in normal and malignant cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60568)
17. [Divergent effects of IL-12 and IL-23 on the production of IL-17 by human T cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60568)
18. [Induction of interactions between CD44 and hyaluronic acid by a short exposure of human T cells to diverse pro-inflammatory mediators](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60568)
19. [The apoptosis and proliferation of SAC-activated B cells by IL-10 are associated with changes in Bcl-2, Bcl-xL, and Mcl-1 expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60568)
20. [Severe combined immunodeficiency due to a specific defect in the production of interleukin-2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60568)
21. [HMGN2: a novel antimicrobial effector molecule of human mononuclear leukocytes?](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60568)
22. [IL-23 modulates CD56+/CD3- NK cell and CD56+/CD3+ NK-like T cell function differentially from IL-12](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60568)
23. Ensembl Release 99
24. Identifiers.org
25. [OpenAlex](https://docs.openalex.org/download-snapshot/snapshot-data-format)