# Interleukin 2 receptor, alpha chain

> mammalian protein found in Mus musculus

**Wikidata**: [Q21495867](https://www.wikidata.org/wiki/Q21495867)  
**Source**: https://4ort.xyz/entity/interleukin-2-receptor-alpha-chain


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P01590)
3. Q20641742
4. [ECM1 controls TH2 cell egress from lymph nodes through re-expression of S1P1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01590)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P01590&geneProductId=UniProtKB:P01590)
6. [Interleukin-2 receptor α chain regulates the size and content of the peripheral lymphoid compartment](http://www.ebi.ac.uk/QuickGO/annotations?protein=P01590&geneProductId=UniProtKB:P01590)
7. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01590)
8. [Interleukin-2 receptor α chain regulates the size and content of the peripheral lymphoid compartment](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01590)
9. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01590)
10. [The BCL2A1 gene as a pre-T cell receptor-induced regulator of thymocyte survival](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01590)
11. [Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01590)
12. [Both the pre-BCR and the IL-7Ralpha are essential for expansion at the pre-BII cell stage in vivo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01590)
13. [Accessory protein-like is essential for IL-18-mediated signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01590)
14. [CD25+CD4+ cells contribute to Th2 polarization during helminth infection by suppressing Th1 response development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01590)
15. [Differential T cell costimulatory requirements in CD28-deficient mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01590)
16. [Missing self-recognition of Ocil/Clr-b by inhibitory NKR-P1 natural killer cell receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01590)
17. [The transcription factor E4BP4 regulates the production of IL-10 and IL-13 in CD4+ T cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01590)
18. [CDK6 kinase activity is required for thymocyte development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01590)
19. [GATA-3 is required for early T lineage progenitor development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01590)
20. [BAFF binding to T cell-expressed BAFF-R costimulates T cell proliferation and alloresponses](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01590)
21. [T lymphocytes amplify the anabolic activity of parathyroid hormone through Wnt10b signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01590)
22. [Cellular mechanisms of fatal early-onset autoimmunity in mice with the T cell-specific targeting of transforming growth factor-beta receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01590)
23. [Where CD4+CD25+ T reg cells impinge on autoimmune diabetes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01590)
24. [Molecular cloning and characterization of murine ICOS and identification of B7h as ICOS ligand](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01590)
25. [Definition and spatial location of mouse interleukin-2 residues that interact with its heterotrimeric receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01590)
26. [Foxn1 regulates lineage progression in cortical and medullary thymic epithelial cells but is dispensable for medullary sublineage divergence](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01590)
27. [Deletion of the mouse T-cell receptor beta gene enhancer blocks alphabeta T-cell development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01590)
28. [Impaired IgG-dependent anaphylaxis and Arthus reaction in Fc gamma RIII (CD16) deficient mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01590)
29. [Enforced expression of GATA3 allows differentiation of IL-17-producing cells, but constrains Th17-mediated pathology](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01590)
30. [GATA-3 regulates the development and function of invariant NKT cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01590)
31. [Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01590)
32. [A function for interleukin 2 in Foxp3-expressing regulatory T cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01590)
33. [Requirement for CARMA1 in antigen receptor-induced NF-kappa B activation and lymphocyte proliferation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01590)
34. [E proteins are required to activate germline transcription of the TCR Vbeta8.2 gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01590)
35. [STAT5 is required for thymopoiesis in a development stage-specific manner](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01590)
36. [Heat-stable antigen/CD24 on mouse T lymphocytes: evidence for a costimulatory function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01590)
37. [Identification of a regulatory T cell specific cell surface molecule that mediates suppressive signals and induces Foxp3 expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01590)
38. [Increased Foxp3(+) CD4(+) regulatory T cells with intact suppressive activity but altered cellular localization in murine lupus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01590)
39. [SCART scavenger receptors identify a novel subset of adult gammadelta T cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01590)
40. [Fas is not essential for lamina propria T lymphocyte homeostasis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01590)
41. ensembl Release 106