# Interleukin 12 receptor subunit beta 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21103375](https://www.wikidata.org/wiki/Q21103375)  
**Source**: https://4ort.xyz/entity/interleukin-12-receptor-subunit-beta-1-q21103375


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P42701)
3. Q20641742
4. [A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42701)
5. [A functional interleukin 12 receptor complex is composed of two beta-type cytokine receptor subunits](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42701)
6. [A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42701&geneProductId=UniProtKB:P42701)
7. [A functional interleukin 12 receptor complex is composed of two beta-type cytokine receptor subunits](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42701&geneProductId=UniProtKB:P42701)
8. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42701&geneProductId=UniProtKB:P42701)
9. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42701)
10. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42701)
11. [Expression cloning of a human IL-12 receptor component. A new member of the cytokine receptor superfamily with strong homology to gp130](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42701)
12. [IL-12 receptor deficiency revisited: IL-23-mediated signaling is also impaired in human genetic IL-12 receptor beta1 deficiency](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42701)
13. [Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42701)
14. [Commensal Gram-negative bacteria prime human dendritic cells for enhanced IL-23 and IL-27 expression and enhanced Th1 development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42701)
15. [Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12](http://www.ebi.ac.uk/QuickGO/annotations?protein=P42701&geneProductId=UniProtKB:P42701)
16. [Regulation of virus-induced IL-12 and IL-23 expression in human macrophages](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P42701)
17. Ensembl Release 99
18. UMLS 2023