# Interferon gamma

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21173277](https://www.wikidata.org/wiki/Q21173277)  
**Source**: https://4ort.xyz/entity/interferon-gamma-q21173277


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P01579)
3. Q20641742
4. [Selective diapedesis of Th1 cells induced by endothelial cell RANTES](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579)
6. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579)
7. [Structure and mechanism of IFN-  antagonism by an orthopoxvirus IFN- -binding protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579)
8. [Crystal structure of a complex between interferon-gamma and its soluble high-affinity receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579)
9. [The structure and activity of a monomeric interferon-gamma:alpha-chain receptor signaling complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579)
10. [Missense mutations in the MEFV gene are associated with fibromyalgia syndrome and correlate with elevated IL-1beta plasma levels](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579)
11. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579)
12. [Identification of a novel serine/threonine kinase and a novel 15-kD protein as potential mediators of the gamma interferon-induced cell death](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579)
13. [Differential effects of insulin-like growth factor-1 and atheroma-associated cytokines on cell proliferation and apoptosis in plaque smooth muscle cells of symptomatic and asymptomatic patients with carotid stenosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579)
14. [HIV-1 p17 and IFN-γ Both Induce Fructose 1,6-Bisposphatase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579)
15. [IFN-gamma-producing human T cells directly induce osteoclastogenesis from human monocytes via the expression of RANKL](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579)
16. [Regulation of bioactive IL-12 production in lipopolysaccharide-stimulated human monocytes is determined by the expression of the p35 subunit](http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579)
17. [Regulation of interleukin-12 expression in human monocytes: selective priming by interferon-gamma of lipopolysaccharide-inducible p35 and p40 genes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579)
18. [TRIM-mediated precision autophagy targets cytoplasmic regulators of innate immunity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579)
19. [Deacetylation of p53 induces autophagy by suppressing Bmf expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579)
20. [Nitric oxide mediates cytokine-induced inhibition of insulin secretion by human islets of Langerhans](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579)
21. [Nitric oxide mediates cytokine-induced inhibition of insulin secretion by human islets of Langerhans](http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579)
22. [The heat shock protein 90-CDC37 chaperone complex is required for signaling by types I and II interferons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579)
23. [The role of CXCL16 and its processing metalloproteinases ADAM10 and ADAM17 in the proliferation and migration of human mesangial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579)
24. [Lung epithelial barrier function and wound healing are decreased by IL-4 and IL-13 and enhanced by IFN-γ](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579)
25. [The killing of Leishmania major by human macrophages is mediated by nitric oxide induced after ligation of the Fc epsilon RII/CD23 surface antigen](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579)
26. [Molecular mechanisms underlying the inhibition of IFN-γ-induced, STAT1-mediated gene transcription in human macrophages by simvastatin and agonists of PPARs and LXRs](http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579)
27. [The heat shock protein 90-CDC37 chaperone complex is required for signaling by types I and II interferons](http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579)
28. [Proinflammatory stimuli induce galectin-9 in human mesenchymal stromal cells to suppress T-cell proliferation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579)
29. [Proinflammatory stimuli induce galectin-9 in human mesenchymal stromal cells to suppress T-cell proliferation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579)
30. [Intestinal epithelial cells secrete exosome-like vesicles](http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579)
31. [A crucial role for Kupffer cell-derived galectin-9 in regulation of T cell immunity in hepatitis C infection](http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579)
32. [Trp-tRNA synthetase bridges DNA-PKcs to PARP-1 to link IFN-γ and p53 signaling](http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579)
33. [A crucial role for Kupffer cell-derived galectin-9 in regulation of T cell immunity in hepatitis C infection](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579)
34. [Negative regulation of IL-17 production by OX40/OX40L interaction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579)
35. [Salmonella induced IL-23 and IL-1beta allow for IL-12 production by monocytes and Mphi1 through induction of IFN-gamma in CD56 NK/NK-like T cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579)
36. [Trp-tRNA synthetase bridges DNA-PKcs to PARP-1 to link IFN-γ and p53 signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579)
37. [Cytokine-stimulated GTP cyclohydrolase I expression in endothelial cells requires coordinated activation of nuclear factor-kappaB and Stat1/Stat3](http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579)
38. [Deacetylation of p53 induces autophagy by suppressing Bmf expression](http://www.ebi.ac.uk/QuickGO/annotations?protein=P01579&geneProductId=UniProtKB:P01579)
39. [Intestinal epithelial cells secrete exosome-like vesicles](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579)
40. [Regulation of bioactive IL-12 production in lipopolysaccharide-stimulated human monocytes is determined by the expression of the p35 subunit](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579)
41. [Regulation of interleukin-12 expression in human monocytes: selective priming by interferon-gamma of lipopolysaccharide-inducible p35 and p40 genes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579)
42. [Molecular mechanisms underlying the inhibition of IFN-γ-induced, STAT1-mediated gene transcription in human macrophages by simvastatin and agonists of PPARs and LXRs](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579)
43. [Cytokine-stimulated GTP cyclohydrolase I expression in endothelial cells requires coordinated activation of nuclear factor-kappaB and Stat1/Stat3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579)
44. [Interferon-{gamma} differentially affects Alzheimer's disease pathologies and induces neurogenesis in triple transgenic-AD mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579)
45. [Activation of microglial cells by beta-amyloid protein and interferon-gamma.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579)
46. [Insulin-like growth factor 2 receptor is an IFNgamma-inducible microglial protein that facilitates intracellular HIV replication: implications for HIV-induced neurocognitive disorders](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579)
47. [Interferon-gamma-dependent cytotoxic activation of human astrocytes and astrocytoma cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01579)
48. Ensembl Release 99