# Interferon gamma inducible protein 16

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21097293](https://www.wikidata.org/wiki/Q21097293)  
**Source**: https://4ort.xyz/entity/interferon-gamma-inducible-protein-16


## References

1. UniProt
2. Q20641742
3. [Differential regulation of estrogen receptor α expression in breast cancer cells by metastasis-associated protein 1](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16666&geneProductId=UniProtKB:Q16666)
4. [Differential regulation of estrogen receptor α expression in breast cancer cells by metastasis-associated protein 1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666)
5. [Human Cytomegalovirus Tegument Protein pUL83 Inhibits IFI16-Mediated DNA Sensing for Immune Evasion](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16666&geneProductId=UniProtKB:Q16666)
6. [Isotypic variants of the interferon-inducible transcriptional repressor IFI 16 arise through differential mRNA splicing](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16666&geneProductId=UniProtKB:Q16666)
7. [IFI 16 gene encodes a nuclear protein whose expression is induced by interferons in human myeloid leukaemia cell lines](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666)
8. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666)
9. [Role of IFI 16, a member of the interferon-inducible p200-protein family, in prostate epithelial cellular senescence](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666)
10. [The intracellular DNA sensor IFI16 gene acts as restriction factor for human cytomegalovirus replication](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666)
11. [The PYRIN domain-only protein POP3 inhibits ALR inflammasomes and regulates responses to infection with DNA viruses](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666)
12. [A member of the Pyrin family, IFI16, is a novel BRCA1-associated protein involved in the p53-mediated apoptosis pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666)
13. [IFI16 is an innate immune sensor for intracellular DNA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666)
14. [Functional interaction between p53 and the interferon-inducible nucleoprotein IFI 16](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666)
15. [Interferon-inducible protein 16: insight into the interaction with tumor suppressor p53](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666)
16. [Androgen receptor auto-regulates its expression by a negative feedback loop through upregulation of IFI16 protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666)
17. [Insights into RNA biology from an atlas of mammalian mRNA-binding proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16666&geneProductId=UniProtKB:Q16666)
18. [Insights into RNA biology from an atlas of mammalian mRNA-binding proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666)
19. [An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666)
20. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16666&geneProductId=UniProtKB:Q16666)
21. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16666&geneProductId=UniProtKB:Q16666)
22. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666)
23. [IFI16 protein mediates the anti-inflammatory actions of the type-I interferons through suppression of activation of caspase-1 by inflammasomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666)
24. [IFI16 Induction by Glucose Restriction in Human Fibroblasts Contributes to Autophagy through Activation of the ATM/AMPK/p53 Pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666)
25. [The IFN-inducible nucleoprotein IFI 16 is expressed in cells of the monocyte lineage, but is rapidly and markedly down-regulated in other myeloid precursor populations](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666)
26. [IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infection](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666)
27. [IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infection](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16666&geneProductId=UniProtKB:Q16666)
28. [The human interferon-inducible protein, IFI 16, is a repressor of transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16666)
29. Ensembl Release 99