# integrin subunit alpha 6

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21107772](https://www.wikidata.org/wiki/Q21107772)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/Integrin_alpha_6)  
**Source**: https://4ort.xyz/entity/integrin-subunit-alpha-6


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P23229)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23229)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P23229&geneProductId=UniProtKB:P23229)
6. [alpha4beta1- and alpha6beta1-integrins are functional receptors for midkine, a heparin-binding growth factor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23229)
7. [NAG-2, a Novel Transmembrane-4 Superfamily (TM4SF) Protein That Complexes with Integrins and Other TM4SF Proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23229)
8. [Association of the VLA alpha 6 subunit with a novel protein. A possible alternative to the common VLA beta 1 subunit on certain cell lines](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23229)
9. [Interaction of Nectin-like Molecule 2 with Integrin α6β4 and Inhibition of Disassembly of Integrin α6β4 from Hemidesmosomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23229)
10. [Direct binding of the EGF-like domain of neuregulin-1 to integrins ({alpha}v{beta}3 and {alpha}6{beta}4) is involved in neuregulin-1/ErbB signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23229)
11. [Cross-talk between integrin α6β4 and insulin-like growth factor-1 receptor (IGF1R) through direct α6β4 binding to IGF1 and subsequent α6β4-IGF1-IGF1R ternary complex formation in anchorage-independent conditions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23229)
12. [E-cadherin interactome complexity and robustness resolved by quantitative proteomics](http://www.ebi.ac.uk/QuickGO/annotations?protein=P23229&geneProductId=UniProtKB:P23229)
13. [E-cadherin interactome complexity and robustness resolved by quantitative proteomics](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23229)
14. [Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P23229&geneProductId=UniProtKB:P23229)
15. [The Androgen Receptor Induces Integrin α6β1 to Promote Prostate Tumor Cell Survival via NF-κB and Bcl-xL Independently of PI3K Signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23229)
16. [Regulation of endodermal differentiation of human embryonic stem cells through integrin-ECM interactions](http://www.ebi.ac.uk/QuickGO/annotations?protein=P23229&geneProductId=UniProtKB:P23229)
17. [Integrin expression and integrin-mediated adhesion in vitro of human multipotent stromal cells (MSCs) to endothelial cells from various blood vessels](http://www.ebi.ac.uk/QuickGO/annotations?protein=P23229&geneProductId=UniProtKB:P23229)
18. [Characterization of integrin engagement during defined human embryonic stem cell culture](http://www.ebi.ac.uk/QuickGO/annotations?protein=P23229&geneProductId=UniProtKB:P23229)
19. [Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance](http://www.ebi.ac.uk/QuickGO/annotations?protein=P23229&geneProductId=UniProtKB:P23229)
20. [Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23229)
21. [Characterization of integrin engagement during defined human embryonic stem cell culture](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23229)
22. [Regulation of endodermal differentiation of human embryonic stem cells through integrin-ECM interactions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23229)
23. [Integrin expression and integrin-mediated adhesion in vitro of human multipotent stromal cells (MSCs) to endothelial cells from various blood vessels](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23229)
24. [Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23229)
25. [Phenotypic spectrum of epidermolysis bullosa associated with α6β4 integrin mutations](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23229)
26. [Odontogenic Ameloblast-associated Protein (ODAM) Mediates Junctional Epithelium Attachment to Teeth via Integrin-ODAM-Rho Guanine Nucleotide Exchange Factor 5 (ARHGEF5)-RhoA Signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23229)
27. [Fas-mediated apoptosis is regulated by the extracellular matrix protein CCN1 (CYR61) in vitro and in vivo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23229)
28. [A homozygous mutation in the integrin alpha6 gene in junctional epidermolysis bullosa with pyloric atresia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23229)
29. [Tumour-suppressive microRNA-29s inhibit cancer cell migration and invasion by targeting laminin-integrin signalling in head and neck squamous cell carcinoma](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23229)
30. Ensembl Release 99
31. Transporter Classification database