# integrin subunit alpha 5

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21110097](https://www.wikidata.org/wiki/Q21110097)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/Integrin_alpha_5)  
**Source**: https://4ort.xyz/entity/integrin-subunit-alpha-5


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P08648)
3. Q20641742
4. [Cooperation between integrin alphavbeta3 and VEGFR2 in angiogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648)
6. [Integrin alpha(v)beta(3) is a pleiotrophin receptor required for pleiotrophin-induced endothelial cell migration through receptor protein tyrosine phosphatase beta/zeta.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648)
7. [Cell adhesion to fibrillin-1 molecules and microfibrils is mediated by alpha 5 beta 1 and alpha v beta 3 integrins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648)
8. [Cartilage oligomeric matrix protein/thrombospondin 5 supports chondrocyte attachment through interaction with integrins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648)
9. [alphaVbeta6 is a novel receptor for human fibrillin-1. Comparative studies of molecular determinants underlying integrin-rgd affinity and specificity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648)
10. [Identification of novel integrin binding partners for calcium and integrin binding protein 1 (CIB1): structural and thermodynamic basis of CIB1 promiscuity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648)
11. [CCN3 (NOV) Is a Novel Angiogenic Regulator of the CCN Protein Family](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648)
12. [Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648)
13. [Endoglin mediates fibronectin/α5β1 integrin and TGF-β pathway crosstalk in endothelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648)
14. [Neuropilin-1/GIPC1 signaling regulates alpha5beta1 integrin traffic and function in endothelial cells.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648)
15. [Basic amino-acid side chains regulate transmembrane integrin signalling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648)
16. [SHARPIN is an endogenous inhibitor of β1-integrin activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648)
17. [Ganglioside GM3 Inhibits Matrix Metalloproteinase-9 Activation and Disrupts Its Association with Integrin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648)
18. [Murine lipid phosphate phosphohydrolase-3 acts as a cell-associated integrin ligand](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648)
19. [Integrin alpha5beta1 and ADAM-17 interact in vitro and co-localize in migrating HeLa cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648)
20. [Integrin cytoplasmic domain-associated protein 1alpha (ICAP-1alpha ) interacts directly with the metastasis suppressor nm23-H2, and both proteins are targeted to newly formed cell adhesion sites upon integrin engagement](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648)
21. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08648&geneProductId=UniProtKB:P08648)
22. [Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08648&geneProductId=UniProtKB:P08648)
23. [Integrin expression and integrin-mediated adhesion in vitro of human multipotent stromal cells (MSCs) to endothelial cells from various blood vessels](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08648&geneProductId=UniProtKB:P08648)
24. [Regulation of endodermal differentiation of human embryonic stem cells through integrin-ECM interactions](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08648&geneProductId=UniProtKB:P08648)
25. [Quantitative proteomics identifies a Dab2/integrin module regulating cell migration](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08648&geneProductId=UniProtKB:P08648)
26. [alphaVbeta6 is a novel receptor for human fibrillin-1. Comparative studies of molecular determinants underlying integrin-rgd affinity and specificity](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08648&geneProductId=UniProtKB:P08648)
27. [Chromosomal localization of the genes for the vitronectin and fibronectin receptors alpha subunits and for platelet glycoproteins IIb and IIIa](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648)
28. [Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08648&geneProductId=UniProtKB:P08648)
29. [Integrin alpha5beta1 and ADAM-17 interact in vitro and co-localize in migrating HeLa cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08648&geneProductId=UniProtKB:P08648)
30. [The WD40-domain containing protein CORO2B is specifically enriched in glomerular podocytes and regulates the ventral actin cytoskeleton.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648)
31. [Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648)
32. [Regulation of endodermal differentiation of human embryonic stem cells through integrin-ECM interactions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648)
33. [Integrin expression and integrin-mediated adhesion in vitro of human multipotent stromal cells (MSCs) to endothelial cells from various blood vessels](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648)
34. [Quantitative proteomics identifies a Dab2/integrin module regulating cell migration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648)
35. [Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648)
36. [MicroRNA-92a controls angiogenesis and functional recovery of ischemic tissues in mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648)
37. [Characterization of integrin engagement during defined human embryonic stem cell culture](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648)
38. [Chromosomal localization of the genes for the vitronectin and fibronectin receptors alpha subunits and for platelet glycoproteins IIb and IIIa](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08648&geneProductId=UniProtKB:P08648)
39. [Role of alphavbeta3 integrin in the activation of vascular endothelial growth factor receptor-2.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648)
40. [A mitochondrial protein, Bit1, mediates apoptosis regulated by integrins and Groucho/TLE corepressors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648)
41. [Adhesion of human haematopoietic (CD34+) stem cells to human liver compartments is integrin and CD44 dependent and modulated by CXCR3 and CXCR4.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648)
42. Ensembl Release 99
43. UMLS 2023