# Integrin linked kinase

> mammalian protein found in Mus musculus

**Wikidata**: [Q21495079](https://www.wikidata.org/wiki/Q21495079)  
**Source**: https://4ort.xyz/entity/integrin-linked-kinase


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O55222)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55222)
5. [Identification and characterization of a mouse protein kinase that is highly homologous to human integrin-linked kinase](http://www.ebi.ac.uk/QuickGO/annotations?protein=O55222&geneProductId=UniProtKB:O55222)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O55222&geneProductId=UniProtKB:O55222)
7. [Interaction of bcl-2 with Paxillin through its BH4 domain is important during ureteric bud branching](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55222)
8. [Thymosin beta4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55222)
9. [Assembly of the PINCH-ILK-CH-ILKBP complex precedes and is essential for localization of each component to cell-matrix adhesion sites](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55222)
10. [Integrin-linked kinase is localized to cell-matrix focal adhesions but not cell-cell adhesion sites and the focal adhesion localization of integrin-linked kinase is regulated by the PINCH-binding ANK repeats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55222)
11. [Alpha-parvin controls vascular mural cell recruitment to vessel wall by regulating RhoA/ROCK signalling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55222)
12. [Stabilization of integrin-linked kinase by the Hsp90-CHIP axis impacts cellular force generation, migration and the fibrotic response](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55222)
13. [Integrin-linked kinase is an adaptor with essential functions during mouse development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55222)
14. [Identification and characterization of a mouse protein kinase that is highly homologous to human integrin-linked kinase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55222)
15. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55222)
16. [Affixin activates Rac1 via betaPIX in C2C12 myoblast](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55222)
17. [Integrin-linked kinase (ILK) binding to paxillin LD1 motif regulates ILK localization to focal adhesions](http://www.ebi.ac.uk/QuickGO/annotations?protein=O55222&geneProductId=UniProtKB:O55222)
18. [Mutations in the Paxillin-binding Site of Integrin-linked Kinase (ILK) Destabilize the Pseudokinase Domain and Cause Embryonic Lethality in Mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=O55222&geneProductId=UniProtKB:O55222)
19. [Thymosin beta4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair](http://www.ebi.ac.uk/QuickGO/annotations?protein=O55222&geneProductId=UniProtKB:O55222)
20. [Assembly of the PINCH-ILK-CH-ILKBP complex precedes and is essential for localization of each component to cell-matrix adhesion sites](http://www.ebi.ac.uk/QuickGO/annotations?protein=O55222&geneProductId=UniProtKB:O55222)
21. [Integrin-linked kinase (ILK) binding to paxillin LD1 motif regulates ILK localization to focal adhesions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55222)
22. [Mutations in the Paxillin-binding Site of Integrin-linked Kinase (ILK) Destabilize the Pseudokinase Domain and Cause Embryonic Lethality in Mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55222)
23. [Integrin-linked kinase is required for radial sorting of axons and Schwann cell remyelination in the peripheral nervous system](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55222)
24. [Dissecting integrin-dependent regulation of neural stem cell proliferation in the adult brain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55222)
25. [Requirement for integrin-linked kinase in neural crest migration and differentiation and outflow tract morphogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55222)
26. [Integrin-linked kinase mediates bone morphogenetic protein 7-dependent renal epithelial cell morphogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55222)
27. [CYR61 regulates BMP-2-dependent osteoblast differentiation through the {alpha}v{beta}3 integrin/integrin-linked kinase/ERK pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55222)
28. [Integrin-linked kinase (ILK) is required for polarizing the epiblast, cell adhesion, and controlling actin accumulation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55222)
29. [Reduced chondrocyte proliferation and chondrodysplasia in mice lacking the integrin-linked kinase in chondrocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55222)
30. ensembl Release 106