# integrin linked kinase

> mammalian protein found in Homo sapiens

**Wikidata**: [Q11913806](https://www.wikidata.org/wiki/Q11913806)  
**Source**: https://4ort.xyz/entity/integrin-linked-kinase-q11913806


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q13418)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13418&geneProductId=UniProtKB:Q13418)
5. [Cloning of an isoform of integrin-linked kinase (ILK) that is upregulated in HT-144 melanoma cells following TGF-beta1 stimulation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13418&geneProductId=UniProtKB:Q13418)
6. [Identification and characterization of a mouse protein kinase that is highly homologous to human integrin-linked kinase](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13418&geneProductId=UniProtKB:Q13418)
7. [The Roles of Two Distinct Regions of PINCH-1 in the Regulation of Cell Attachment and Spreading](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13418&geneProductId=UniProtKB:Q13418)
8. [The structural basis of integrin-linked kinase-PINCH interactions](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13418&geneProductId=UniProtKB:Q13418)
9. [Modulation of integrin signal transduction by ILKAP, a protein phosphatase 2C associating with the integrin-linked kinase, ILK1.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13418&geneProductId=UniProtKB:Q13418)
10. [Substrate-Trapped Interactors of PHD3 and FIH Cluster in Distinct Signaling Pathways](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13418&geneProductId=UniProtKB:Q13418)
11. [Integrin-linked kinase interacts with caspase-9 and -8 in an adhesion-dependent manner for promoting radiation-induced apoptosis in human leukemia cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13418&geneProductId=UniProtKB:Q13418)
12. [Rictor and integrin-linked kinase interact and regulate Akt phosphorylation and cancer cell survival](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13418&geneProductId=UniProtKB:Q13418)
13. [A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13418&geneProductId=UniProtKB:Q13418)
14. [Interaction of smoothened with integrin-linked kinase in primary cilia mediates Hedgehog signalling](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13418&geneProductId=UniProtKB:Q13418)
15. [Next-generation sequencing to generate interactome datasets](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13418&geneProductId=UniProtKB:Q13418)
16. [Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13418&geneProductId=UniProtKB:Q13418)
17. [A human interactome in three quantitative dimensions organized by stoichiometries and abundances](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13418&geneProductId=UniProtKB:Q13418)
18. [Assembly of the PINCH-ILK-CH-ILKBP complex precedes and is essential for localization of each component to cell-matrix adhesion sites](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13418&geneProductId=UniProtKB:Q13418)
19. [Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13418&geneProductId=UniProtKB:Q13418)
20. [Towards a proteome-scale map of the human protein–protein interaction network](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13418&geneProductId=UniProtKB:Q13418)
21. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13418&geneProductId=UniProtKB:Q13418)
22. [Phosphorylation and interaction of myopodin by integrin-link kinase lead to suppression of cell growth and motility in prostate cancer cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13418&geneProductId=UniProtKB:Q13418)
23. [Posttranslational hydroxylation of ankyrin repeats in IkappaB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH)](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13418&geneProductId=UniProtKB:Q13418)
24. [Interaction of integrin-linked kinase with the kidney chloride/bicarbonate exchanger, kAE1](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13418&geneProductId=UniProtKB:Q13418)
25. [EphA1 interacts with integrin-linked kinase and regulates cell morphology and motility](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13418&geneProductId=UniProtKB:Q13418)
26. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13418&geneProductId=UniProtKB:Q13418)
27. [Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13418&geneProductId=UniProtKB:Q13418)
28. [Type I collagen promotes epithelial-mesenchymal transition through ILK-dependent activation of NF-kappaB and LEF-1](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13418&geneProductId=UniProtKB:Q13418)
29. [Regulation of cell adhesion and anchorage-dependent growth by a new beta 1-integrin-linked protein kinase](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13418&geneProductId=UniProtKB:Q13418)
30. [Platelet Proteome Analysis Reveals Integrin-dependent Aggregation Defects in Patients with Myelodysplastic Syndromes](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13418&geneProductId=UniProtKB:Q13418)
31. [Thymosin beta4 inhibits TNF-alpha-induced NF-kappaB activation, IL-8 expression, and the sensitizing effects by its partners PINCH-1 and ILK](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13418&geneProductId=UniProtKB:Q13418)
32. Ensembl Release 99