# Integral membrane protein 2B

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21173193](https://www.wikidata.org/wiki/Q21173193)  
**Source**: https://4ort.xyz/entity/integral-membrane-protein-2b-q21173193


## References

1. UniProt
2. Q20641742
3. [CD74 interacts with APP and suppresses the production of Abeta](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y287&geneProductId=UniProtKB:Q9Y287)
4. [Regulated intramembrane proteolysis of Bri2 (Itm2b) by ADAM10 and SPPL2a/SPPL2b](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y287)
5. [BRI2 interacts with amyloid precursor protein (APP) and regulates amyloid beta (Abeta) production](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y287)
6. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y287)
7. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y287)
8. [CD74 interacts with APP and suppresses the production of Abeta](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y287)
9. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y287)
10. [Furin mediates enhanced production of fibrillogenic ABri peptides in familial British dementia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y287)
11. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y287&geneProductId=UniProtKB:Q9Y287)
12. [Substrate requirements for SPPL2b-dependent regulated intramembrane proteolysis](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y287&geneProductId=UniProtKB:Q9Y287)
13. [The α-Helical Content of the Transmembrane Domain of the British Dementia Protein-2 (Bri2) Determines Its Processing by Signal Peptide Peptidase-like 2b (SPPL2b)](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y287&geneProductId=UniProtKB:Q9Y287)
14. [Proteomic analysis of podocyte exosome-enriched fraction from normal human urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y287&geneProductId=UniProtKB:Q9Y287)
15. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y287&geneProductId=UniProtKB:Q9Y287)
16. [Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y287&geneProductId=UniProtKB:Q9Y287)
17. [In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y287&geneProductId=UniProtKB:Q9Y287)
18. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y287&geneProductId=UniProtKB:Q9Y287)
19. [BRI2 (ITM2b) Inhibits A Deposition In Vivo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y287)
20. [The α-Helical Content of the Transmembrane Domain of the British Dementia Protein-2 (Bri2) Determines Its Processing by Signal Peptide Peptidase-like 2b (SPPL2b)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y287)
21. [Substrate requirements for SPPL2b-dependent regulated intramembrane proteolysis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y287)
22. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y287)
23. [Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y287)
24. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y287)
25. [In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y287)
26. [A stop-codon mutation in the BRI gene associated with familial British dementia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y287)
27. [BRI2 interacts with amyloid precursor protein (APP) and regulates amyloid beta (Abeta) production](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y287&geneProductId=UniProtKB:Q9Y287)
28. [BRI2 (ITM2b) Inhibits A Deposition In Vivo](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y287&geneProductId=UniProtKB:Q9Y287)
29. ensembl Release 93
30. Transporter Classification database