# Insulin like growth factor binding protein 3

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21110108](https://www.wikidata.org/wiki/Q21110108)  
**Source**: https://4ort.xyz/entity/insulin-like-growth-factor-binding-protein-3


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P17936)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936)
5. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936)
6. [Role of insulin-like growth factor binding protein-3 (IGFBP-3) in the differentiation of primary human adult skeletal myoblasts](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936)
7. [Insulin-like growth factor-binding protein-3 activates a phosphotyrosine phosphatase. Effects on the insulin-like growth factor signaling pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936)
8. [Substitutions for hydrophobic amino acids in the N-terminal domains of IGFBP-3 and -5 markedly reduce IGF-I binding and alter their biologic actions](http://www.ebi.ac.uk/QuickGO/annotations?protein=P17936&geneProductId=UniProtKB:P17936)
9. [Insulin-like growth factor-independent effects mediated by a C-terminal metal-binding domain of insulin-like growth factor binding protein-3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936)
10. [Interaction between the Alzheimer's survival peptide humanin and insulin-like growth factor-binding protein 3 regulates cell survival and apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936)
11. [Inhibition of Insulin Receptor Activation by Insulin-like Growth Factor Binding Proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936)
12. [Identification of a Novel Cell Death Receptor Mediating IGFBP-3-induced Anti-tumor Effects in Breast and Prostate Cancer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936)
13. [The role of insulin-like growth factor binding protein-3 in the breast cancer cell response to DNA-damaging agents](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936)
14. [Substitutions for hydrophobic amino acids in the N-terminal domains of IGFBP-3 and -5 markedly reduce IGF-I binding and alter their biologic actions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936)
15. [Insulin-like growth factor (IGF)-binding protein 5 forms an alternative ternary complex with IGFs and the acid-labile subunit](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936)
16. [The human plasma proteome: a nonredundant list developed by combination of four separate sources](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936)
17. [Contribution of the orphan nuclear receptor Nur77 to the apoptotic action of IGFBP-3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936)
18. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P17936&geneProductId=UniProtKB:P17936)
19. [Ethnic disparity in the relationship between obesity and plasma insulin-like growth factors: the multiethnic cohort](http://www.ebi.ac.uk/QuickGO/annotations?protein=P17936&geneProductId=UniProtKB:P17936)
20. [Ethnic disparity in the relationship between obesity and plasma insulin-like growth factors: the multiethnic cohort](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936)
21. [The requirement of pax6 for postnatal eye development: evidence from experimental mouse chimeras](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936)
22. [Insulin-like growth factor binding protein-3 mediates tumor necrosis factor-alpha-induced apoptosis: role of Bcl-2 phosphorylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936)
23. [NKX3.1 activates expression of insulin-like growth factor binding protein-3 to mediate insulin-like growth factor-I signaling and cell proliferation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17936)
24. Ensembl Release 99
25. [Identifiers.org](https://registry.identifiers.org/registry/uniprot)