# Inhibitor of kappaB kinase gamma

> mammalian protein found in Mus musculus

**Wikidata**: [Q14908211](https://www.wikidata.org/wiki/Q14908211)  
**Source**: https://4ort.xyz/entity/inhibitor-of-kappab-kinase-gamma


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O88522)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88522)
5. [Telomere-independent Rap1 is an IKK adaptor and regulates NF-kappaB-dependent gene expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88522)
6. [Identification of a novel tissue-specific transcriptional activator FESTA as a protein that interacts with the transcription elongation factor S-II](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88522)
7. [Pellino3 ubiquitinates RIP2 and mediates Nod2-induced signaling and protective effects in colitis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88522)
8. [Optineurin negatively regulates TNFalpha- induced NF-kappaB activation by competing with NEMO for ubiquitinated RIP](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88522)
9. [Inhibition of IkappaB kinase by vaccinia virus virulence factor B14](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88522)
10. [USP10 inhibits genotoxic NF-κB activation by MCPIP1-facilitated deubiquitination of NEMO](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88522)
11. [Interleukin-23 production in dendritic cells is negatively regulated by protein phosphatase 2A](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88522)
12. [Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88522)
13. [Signal processing by its coil zipper domain activates IKK gamma](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88522)
14. [The RET/PTC3 oncogene activates classical NF-κB by stabilizing NIK](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88522)
15. [NEMO specifically recognizes K63-linked poly-ubiquitin chains through a new bipartite ubiquitin-binding domain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88522)
16. [LUBAC regulates NF-κB activation upon genotoxic stress by promoting linear ubiquitination of NEMO](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88522)
17. [SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88522)
18. [NLRC5 negatively regulates the NF-kappaB and type I interferon signaling pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88522)
19. [Mechanism Underlying I B Kinase Activation Mediated by the Linear Ubiquitin Chain Assembly Complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88522)
20. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O88522&geneProductId=UniProtKB:O88522)
21. [Optineurin negatively regulates TNFalpha- induced NF-kappaB activation by competing with NEMO for ubiquitinated RIP](http://www.ebi.ac.uk/QuickGO/annotations?protein=O88522&geneProductId=UniProtKB:O88522)
22. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88522)
23. [SASH1 Is a Scaffold Molecule in Endothelial TLR4 Signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88522)
24. [Segregation of NF-kappaB activation through NEMO/IKKgamma by Tax and TNFalpha: implications for stimulus-specific interruption of oncogenic signaling](http://www.ebi.ac.uk/QuickGO/annotations?protein=O88522&geneProductId=UniProtKB:O88522)
25. [Segregation of NF-kappaB activation through NEMO/IKKgamma by Tax and TNFalpha: implications for stimulus-specific interruption of oncogenic signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88522)
26. [IkappaB kinase signaling is essential for maintenance of mature B cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88522)
27. [The E3 ligase parkin maintains mitochondrial integrity by increasing linear ubiquitination of NEMO](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88522)
28. [IκB kinase complex (IKK) triggers detachment-induced autophagy in mammary epithelial cells independently of the PI3K-AKT-MTORC1 pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88522)
29. ensembl Release 106