# Il-1R–Associated kinase 4 deficiency

> Interleukin-1 receptor-associated kinase-4 (IRAK-4) deficiency is an immunodeficiency associated with increased susceptibility to invasive infections caused by pyogenic bacteria

**Wikidata**: [Q5996465](https://www.wikidata.org/wiki/Q5996465)  
**Source**: https://4ort.xyz/entity/il-1r-associated-kinase-4-deficiency


## References

1. Monarch Disease Ontology release 2018-06-29
2. Pyogenic Bacterial Infections in Humans with IRAK-4 Deficiency
3. [Open Targets Platform](https://platform.opentargets.org/evidence/ENSG00000198001/MONDO_0011888)
4. [Open Targets Platform](https://platform.opentargets.org/evidence/ENSG00000198001/Orphanet_70592)