IKAROS family zinc finger 4
type: Thing
description: mammalian protein found in Homo sapiens
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P361
  value: Zinc finger C2H2 superfamily
additional property: PropertyValue
  property ID: P361
  value: Zinc finger C2H2-type, protein family
additional property: PropertyValue
  property ID: P527
  value: Zinc finger C2H2-type
additional property: PropertyValue
  property ID: P637
  value: NP_071910
additional property: PropertyValue
  property ID: P637
  value: XP_005269143
additional property: PropertyValue
  property ID: P637
  value: XP_005269146
additional property: PropertyValue
  property ID: P638
  value: 2MA7
additional property: PropertyValue
  property ID: P680
  value: DNA-binding transcription factor activity
additional property: PropertyValue
  property ID: P680
  value: nucleic acid binding
additional property: PropertyValue
  property ID: P680
  value: sequence-specific DNA binding
additional property: PropertyValue
  property ID: P681
  value: nucleus
additional property: PropertyValue
  property ID: P681
  value: nucleoplasm
additional property: PropertyValue
  property ID: P681
  value: nuclear body
additional property: PropertyValue
  property ID: P682
  value: negative regulation of transcription, DNA-templated
additional property: PropertyValue
  property ID: P682
  value: regulation of transcription, DNA-templated
additional property: PropertyValue
  property ID: P682
  value: transcription, DNA-templated
additional property: PropertyValue
  property ID: P702
  value: IKZF4
additional property: PropertyValue
  property ID: P703
  value: Homo sapiens
additional property: PropertyValue
  property ID: P705
  value: ENSP00000262032
additional property: PropertyValue
  property ID: P705
  value: ENSP00000412101
additional property: PropertyValue
  property ID: P705
  value: ENSP00000448419
confidence:
  popularity graph score:
    score: 0.001
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 10
      unique citations norm: 0.004
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 10
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: Q9H2S9
    source count: 1
    confidence: 0.2
  P361:
    value: Q41797357
    source count: 1
    confidence: 0.2
    value label: Zinc finger C2H2 superfamily
  P361:
    value: Q83164179
    source count: 1
    confidence: 0.2
    value label: Zinc finger C2H2-type, protein family
  P527:
    value: Q24785163
    source count: 1
    confidence: 0.2
    value label: Zinc finger C2H2-type
  P637:
    value: NP_071910
    source count: 1
    confidence: 0.2
  P637:
    value: XP_005269143
    source count: 1
    confidence: 0.2
  P637:
    value: XP_005269146
    source count: 1
    confidence: 0.2
  P637:
    value: XP_011536966
    source count: 1
    confidence: 0.2
  P637:
    value: XP_011536971
    source count: 1
    confidence: 0.2
  P638:
    value: 2MA7
    source count: 1
    confidence: 0.2
  P680:
    value: Q14817979
    source count: 1
    confidence: 0.2
    value label: DNA-binding transcription factor activity
  P680:
    value: Q14864825
    source count: 1
    confidence: 0.2
    value label: nucleic acid binding
  P680:
    value: Q14818107
    source count: 1
    confidence: 0.2
    value label: sequence-specific DNA binding
  P680:
    value: Q14633858
    source count: 1
    confidence: 0.2
    value label: DNA binding
  P680:
    value: Q14888050
    source count: 1
    confidence: 0.2
    value label: bHLH transcription factor binding
  P681:
    value: Q40260
    source count: 2
    confidence: 0.4
    value label: nucleus
  P681:
    value: Q14817956
    source count: 1
    confidence: 0.2
    value label: nucleoplasm
  P681:
    value: Q14817965
    source count: 1
    confidence: 0.2
    value label: nuclear body
  P681:
    value: Q22325163
    source count: 1
    confidence: 0.2
    value label: protein-containing complex
  P681:
    value: Q14817956
    source count: 2
    confidence: 0.4
    value label: nucleoplasm
  P682:
    value: Q14633919
    source count: 2
    confidence: 0.4
    value label: negative regulation of transcription, DNA-templated
  P682:
    value: Q14633883
    source count: 1
    confidence: 0.2
    value label: regulation of transcription, DNA-templated
  P682:
    value: Q14763010
    source count: 1
    confidence: 0.2
    value label: transcription, DNA-templated
  P682:
    value: Q14818068
    source count: 2
    confidence: 0.4
    value label: positive regulation of transcription by RNA polymerase II

value: Q14860815
source count: 1
confidence: 0.2
value label: protein homooligomerization

value: Q18045645
source count: 1
confidence: 0.2
value label: IKZF4

value: Q15978631
source count: 1
confidence: 0.2
value label: Homo sapiens

value: ENSP00000262032
source count: 1
confidence: 0.2

value: ENSP00000412101
source count: 1
confidence: 0.2

value: ENSP00000448419
source count: 1
confidence: 0.2

value: ENSP00000449168
source count: 1
confidence: 0.2

value: ENSP00000449857
source count: 1
confidence: 0.2

source: Eos and pegasus, two members of the Ikaros family of proteins with distinct DNA binding activities
stated in qid: Q24290205
retrieved: 2018-03-27

source: GOA
stated in qid: Q28018111
retrieved: 2019-04-08

source: GOA
stated in qid: Q28018111
retrieved: 2018-03-27

source: Structural studies on a protein-binding zinc-finger domain of Eos reveal both similarities and differences to classical zinc fingers
stated in qid: Q28910490
retrieved: 2019-04-08

source: Eos and pegasus, two members of the Ikaros family of proteins with distinct DNA binding activities
stated in qid: Q24290205
retrieved: 2019-04-08

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2019-04-08

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2019-11-13

source: Q20641742
stated in qid: Q20641742
retrieved: 2020-05-30

source: Ensembl Release 99
stated in qid: Q83867711

wikidata id: Q21120655
domain: protein
level: standard
html url: https://4ort.xyz/entity/ikaros-family-zinc-finger-4-q21120655
markdown url: https://4ort.xyz/entity/ikaros-family-zinc-finger-4-q21120655.md
facts url summary: https://4ort.xyz/entity/ikaros-family-zinc-finger-4-q21120655/facts.json
facts url standard: https://4ort.xyz/entity/ikaros-family-zinc-finger-4-q21120655/facts.json
facts url full: https://4ort.xyz/entity/ikaros-family-zinc-finger-4-q21120655/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-09T14:32:11.068669Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T15:12:06.018882+00:00Z