IKAROS family zinc finger 3
type: Thing
description: mammalian protein found in Homo sapiens
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P361
  value: Zinc finger C2H2 superfamily
additional property: PropertyValue
  property ID: P361
  value: Zinc finger C2H2-type, protein family
additional property: PropertyValue
  property ID: P527
  value: Zinc finger C2H2-type
additional property: PropertyValue
  property ID: P637
  value: NP_001244337
additional property: PropertyValue
  property ID: P637
  value: NP_001244338
additional property: PropertyValue
  property ID: P637
  value: NP_001244339
additional property: PropertyValue
  property ID: P680
  value: sequence-specific DNA binding
additional property: PropertyValue
  property ID: P680
  value: DNA binding
additional property: PropertyValue
  property ID: P680
  value: RNA polymerase II transcription regulatory region sequence-specific DNA binding
additional property: PropertyValue
  property ID: P681
  value: cytoplasm
additional property: PropertyValue
  property ID: P681
  value: plasma membrane
additional property: PropertyValue
  property ID: P681
  value: nucleus
additional property: PropertyValue
  property ID: P682
  value: regulation of apoptotic process
additional property: PropertyValue
  property ID: P682
  value: regulation of transcription, DNA-templated
additional property: PropertyValue
  property ID: P682
  value: regulation of transcription by RNA polymerase II
additional property: PropertyValue
  property ID: P702
  value: IKZF3
additional property: PropertyValue
  property ID: P703
  value: Homo sapiens
additional property: PropertyValue
  property ID: P705
  value: ENSP00000341977
additional property: PropertyValue
  property ID: P705
  value: ENSP00000344471
additional property: PropertyValue
  property ID: P705
  value: ENSP00000344544
confidence:
  popularity graph score:
    score: 0.003
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 19
      unique citations norm: 0.007
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 19
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: Q9UKT9
    source count: 1
    confidence: 0.2
  P361:
    value: Q41797357
    source count: 1
    confidence: 0.2
    value label: Zinc finger C2H2 superfamily
  P361:
    value: Q83164179
    source count: 1
    confidence: 0.2
    value label: Zinc finger C2H2-type, protein family
  P527:
    value: Q24785163
    source count: 1
    confidence: 0.2
    value label: Zinc finger C2H2-type
  P637:
    value: NP_001244337
    source count: 1
    confidence: 0.2
  P637:
    value: NP_001244338
    source count: 1
    confidence: 0.2
  P637:
    value: NP_001244339
    source count: 1
    confidence: 0.2
  P637:
    value: NP_001244340
    source count: 1
    confidence: 0.2
  P637:
    value: NP_001244341
    source count: 1
    confidence: 0.2
  P680:
    value: Q14818107
    source count: 2
    confidence: 0.4
    value label: sequence-specific DNA binding
  P680:
    value: Q14633858
    source count: 1
    confidence: 0.2
    value label: DNA binding
  P680:
    value: Q14864823
    source count: 1
    confidence: 0.2
    value label: RNA polymerase II transcription regulatory region sequence-specific DNA binding
  P680:
    value: Q14762996
    source count: 1
    confidence: 0.2
    value label: protein homodimerization activity
  P680:
    value: Q14817979
    source count: 1
    confidence: 0.2
    value label: DNA-binding transcription factor activity
  P681:
    value: Q79899
    source count: 4
    confidence: 0.8
    value label: cytoplasm
  P681:
    value: Q29548
    source count: 1
    confidence: 0.2
    value label: plasma membrane
  P681:
    value: Q40260
    source count: 4
    confidence: 0.8
    value label: nucleus
  P681:
    value: Q14817956
    source count: 1
    confidence: 0.2
    value label: nucleoplasm
  P681:
    value: Q220599
    source count: 1
    confidence: 0.2
    value label: cytosol
  P682:
    value: Q14633911
    source count: 1
    confidence: 0.2
    value label: regulation of apoptotic process
  P682:
    value: Q14633883
    source count: 1
    confidence: 0.2
    value label: regulation of transcription, DNA-templated
  P682:
    value: Q14852032
    source count: 1
    confidence: 0.2
    value label: regulation of transcription by RNA polymerase II
  P682:
    value: Q14864650
    source count: 1
    confidence: 0.2
    value label: transcription by RNA polymerase II
  P682:
    value: Q14763010
    source count: 1
    confidence: 0.2
    value label: transcription, DNA-templated

value: Q18036500
source count: 1
confidence: 0.2
value label: IKZF3

value: Q15978631
source count: 1
confidence: 0.2
value label: Homo sapiens

value: ENSP00000341977
source count: 1
confidence: 0.2

value: ENSP00000344471
source count: 1
confidence: 0.2

value: ENSP00000344544
source count: 1
confidence: 0.2

value: ENSP00000345622
source count: 1
confidence: 0.2

value: ENSP00000367179
source count: 1
confidence: 0.2

source: GOA
stated in qid: Q28018111
retrieved: 2019-04-08

source: Combinatorial effects of splice variants modulate function of Aiolos
stated in qid: Q24321807
retrieved: 2019-04-08

source: Human aiolos, an ikaros-related zinc finger DNA binding protein: cDNA cloning, tissue expression pattern, and chromosomal mapping
stated in qid: Q22010766
retrieved: 2018-07-16

source: Aiolos transcription factor controls cell death in T cells by regulating Bcl-2 expression and its cellular localization
stated in qid: Q22009996
retrieved: 2019-04-08

source: The Association of Aiolos Transcription Factor and Bcl-xL Is Involved in the Control of Apoptosis
stated in qid: Q24291916
retrieved: 2019-04-08

source: Activation of the aryl hydrocarbon receptor induces human type 1 regulatory T cell-like and Foxp3(+) regulatory T cells
stated in qid: Q24293709
retrieved: 2019-04-08

source: Next-generation sequencing to generate interactome datasets
stated in qid: Q24300269
retrieved: 2019-04-08

source: A proteome-scale map of the human interactome network
stated in qid: Q24307146
retrieved: 2019-04-08

source: Widespread macromolecular interaction perturbations in human genetic disorders
stated in qid: Q28771729
retrieved: 2019-04-08

source: Pooled-matrix protein interaction screens using Barcode Fusion Genetics
stated in qid: Q28114947
retrieved: 2019-04-08

source: Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing
stated in qid: Q36940515
retrieved: 2019-04-08

source: A census of human transcription factors: function, expression and evolution
stated in qid: Q29622841
retrieved: 2019-04-08

source: Human aiolos, an ikaros-related zinc finger DNA binding protein: cDNA cloning, tissue expression pattern, and chromosomal mapping
stated in qid: Q22010766
retrieved: 2019-04-08

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2019-04-08

source: GOA
stated in qid: Q28018111
retrieved: 2018-07-16

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2019-11-13

source: Q20641742
stated in qid: Q20641742
retrieved: 2020-05-30

source: Ensembl Release 99
stated in qid: Q83867711

wikidata id: Q21115201
domain: protein
level: standard
html url: https://4ort.xyz/entity/ikaros-family-zinc-finger-3-q21115201
markdown url: https://4ort.xyz/entity/ikaros-family-zinc-finger-3-q21115201.md
facts url summary: https://4ort.xyz/entity/ikaros-family-zinc-finger-3-q21115201/facts.json
facts url standard: https://4ort.xyz/entity/ikaros-family-zinc-finger-3-q21115201/facts.json
facts url full: https://4ort.xyz/entity/ikaros-family-zinc-finger-3-q21115201/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-09T10:47:03.072020Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T15:12:06.018882+00:00Z