# Hypoxanthine phosphoribosyltransferase 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q418137](https://www.wikidata.org/wiki/Q418137)  
**Source**: https://4ort.xyz/entity/hypoxanthine-phosphoribosyltransferase-1-q418137


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P00492)
3. Q20641742
4. Freebase Data Dumps. 2013
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00492)
6. [The crystal structure of human hypoxanthine-guanine phosphoribosyltransferase with bound GMP](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00492)
7. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P00492&geneProductId=UniProtKB:P00492)
8. [Isolation and characterization of a full-length expressible cDNA for human hypoxanthine phosphoribosyl transferase](http://www.ebi.ac.uk/QuickGO/annotations?protein=P00492&geneProductId=UniProtKB:P00492)
9. [Inhibition of hypoxanthine-guanine phosphoribosyltransferase by acyclic nucleoside phosphonates: a new class of antimalarial therapeutics](http://www.ebi.ac.uk/QuickGO/annotations?protein=P00492&geneProductId=UniProtKB:P00492)
10. [Catalysis in Human Hypoxanthine-Guanine Phosphoribosyltransferase: Asp 137 Acts as a General Acid/Base](http://www.ebi.ac.uk/QuickGO/annotations?protein=P00492&geneProductId=UniProtKB:P00492)
11. [Human hypoxanthine-guanine phosphoribosyltransferase. Evidence for tetrameric structure](http://www.ebi.ac.uk/QuickGO/annotations?protein=P00492&geneProductId=UniProtKB:P00492)
12. [Inhibition of hypoxanthine-guanine phosphoribosyltransferase by acyclic nucleoside phosphonates: a new class of antimalarial therapeutics](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00492)
13. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00492)
14. [An empirical framework for binary interactome mapping](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00492)
15. [Widespread macromolecular interaction perturbations in human genetic disorders](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00492)
16. [Towards a proteome-scale map of the human protein–protein interaction network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00492)
17. [The 2.0 A structure of human hypoxanthine-guanine phosphoribosyltransferase in complex with a transition-state analog inhibitor](http://www.ebi.ac.uk/QuickGO/annotations?protein=P00492&geneProductId=UniProtKB:P00492)
18. [The 2.0 A structure of human hypoxanthine-guanine phosphoribosyltransferase in complex with a transition-state analog inhibitor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00492)
19. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00492)
20. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=P00492&geneProductId=UniProtKB:P00492)
21. [Catalysis in Human Hypoxanthine-Guanine Phosphoribosyltransferase: Asp 137 Acts as a General Acid/Base](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00492)
22. [Isolation and characterization of a full-length expressible cDNA for human hypoxanthine phosphoribosyl transferase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00492)
23. [Proteomic analysis of podocyte exosome-enriched fraction from normal human urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=P00492&geneProductId=UniProtKB:P00492)
24. [MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P00492&geneProductId=UniProtKB:P00492)
25. [MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00492)
26. [Purine metabolism in female heterozygotes for hypoxanthine-guanine phosphoribosyltransferase deficiency](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00492)
27. [Purine metabolism in female heterozygotes for hypoxanthine-guanine phosphoribosyltransferase deficiency](http://www.ebi.ac.uk/QuickGO/annotations?protein=P00492&geneProductId=UniProtKB:P00492)
28. [The crystal structure of free human hypoxanthine-guanine phosphoribosyltransferase reveals extensive conformational plasticity throughout the catalytic cycle](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00492)
29. [Dopamine transporters are markedly reduced in Lesch-Nyhan disease in vivo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00492)
30. Ensembl Release 99
31. Identifiers.org