# hypogonadotropic hypogonadism 6 with or without anosmia

> hypogonadotropic hypogonadism that is characterized by autosomal dominant inheritance and has material basis in heterozygous mutation in the FGF8 gene on chromosome 10q24, sometimes in association with mutation in another gene

**Wikidata**: [Q32038861](https://www.wikidata.org/wiki/Q32038861)  
**Source**: https://4ort.xyz/entity/hypogonadotropic-hypogonadism-6-with-or-without-anosmia


## References

1. Disease Ontology
2. Monarch Disease Ontology release 2018-06-29
3. UniProt
4. Decreased FGF8 signaling causes deficiency of gonadotropin-releasing hormone in humans and mice
5. [Open Targets Platform](https://platform.opentargets.org/evidence/ENSG00000107831/MONDO_0012988)
6. [Identifiers.org](https://registry.identifiers.org/registry/doid)