# Hypocretin neuropeptide precursor

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28561772](https://www.wikidata.org/wiki/Q28561772)  
**Source**: https://4ort.xyz/entity/hypocretin-neuropeptide-precursor


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O55232)
3. Q20641742
4. [Orexin-A augments voltage-gated Ca2+ currents and synergistically increases growth hormone (GH) secretion with GH-releasing hormone in primary cultured ovine somatotropes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55232)
5. [Postsynaptic excitation of prefrontal cortical pyramidal neurons by hypocretin-1/orexin A through the inhibition of potassium currents](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55232)
6. [Orexin receptor type-1 couples exclusively to pertussis toxin-insensitive G-proteins, while orexin receptor type-2 couples to both pertussis toxin-sensitive and -insensitive G-proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55232)
7. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55232)
8. [Pattern of orexin expression and direct biological actions of orexin-a in rat testis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55232)
9. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55232)
10. [The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55232)
11. [Clozapine blocks sympathetic and thermogenic reactions induced by orexin A in rat](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55232)
12. [Orexin neurons project to diverse sympathetic outflow systems](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55232)
13. [Mechanisms of orexin A-evoked changes of intracellular calcium in primary cultured cortical neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55232)
14. [Gastrointestinal-projecting neurones in the dorsal motor nucleus of the vagus exhibit direct and viscerotopically organized sensitivity to orexin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55232)
15. [Orexin expression and function: glucocorticoid manipulation, stress, and feeding studies](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55232)
16. [Stimulation of cortical acetylcholine release by orexin A](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55232)
17. [Dual regulatory effects of orexins on sympathetic nerve activity innervating brown adipose tissue in rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55232)
18. [Orexin receptor-1 mediates brown fat developmental differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55232)
19. ensembl Release 106