# Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28558040](https://www.wikidata.org/wiki/Q28558040)  
**Source**: https://4ort.xyz/entity/hyperpolarization-activated-cyclic-nucleotide-gated-potassium-and-sodium-channel-2-q28558040


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q9JKA9)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JKA9)
5. [Hyperpolarization-activated, cyclic nucleotide-gated HCN2 cation channel forms a protein assembly with multiple neuronal scaffold proteins in distinct modes of protein-protein interaction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JKA9)
6. [HCN2 and HCN4 isoforms self-assemble and co-assemble with equal preference to form functional pacemaker channels](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JKA9)
7. [Activity-dependent heteromerization of the hyperpolarization-activated, cyclic-nucleotide gated (HCN) channels: role of N-linked glycosylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JKA9)
8. [HCN1 and HCN2 proteins are expressed in cochlear hair cells: HCN1 can form a ternary complex with protocadherin 15 CD3 and F-actin-binding filamin A or can interact with HCN2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JKA9)
9. [Differential expression of HCN subunits alters voltage-dependent gating of h-channels in CA1 pyramidal neurons from dorsal and ventral hippocampus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JKA9)
10. [Inflammation-induced increase in hyperpolarization-activated, cyclic nucleotide-gated channel protein in trigeminal ganglion neurons and the effect of buprenorphine](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JKA9)
11. [Distribution of voltage-gated potassium and hyperpolarization-activated channels in sensory afferent fibers in the rat carotid body](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JKA9)
12. [Reciprocal modulation of I (h) and I (TASK) in thalamocortical relay neurons by halothane](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JKA9)
13. [Functional presynaptic HCN channels in the rat globus pallidus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JKA9)
14. [Postnatal expression pattern of HCN channel isoforms in thalamic neurons: relationship to maturation of thalamocortical oscillations.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JKA9)
15. [Age-related down-regulation of HCN channels in rat sinoatrial node](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JKA9)
16. [Thyroid hormone regulates hyperpolarization-activated cyclic nucleotide-gated channel (HCN2) mRNA in the rat heart](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JKA9)
17. [Declines in levels of hyperpolarization-activated cation (HCN) channels in the rat ovary after cisplatin exposure](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JKA9)
18. [Aldosterone modulates I(f) current through gene expression in cultured neonatal rat ventricular myocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JKA9)
19. ensembl Release 106