HTRA1
type: Thing
description: protein-coding gene in the species Homo sapiens
additional property: PropertyValue
  property ID: P18
  value: Protein HTRA1 PDB 2JOA.png
additional property: PropertyValue
  property ID: P31
  value: gene
additional property: PropertyValue
  property ID: P279
  value: protein-coding gene
additional property: PropertyValue
  property ID: P351
  value: 5654
additional property: PropertyValue
  property ID: P353
  value: HTRA1
additional property: PropertyValue
  property ID: P354
  value: 9476
additional property: PropertyValue
  property ID: P492
  value: 602194
additional property: PropertyValue
  property ID: P593
  value: 31114
additional property: PropertyValue
  property ID: P594
  value: ENSG00000166033
additional property: PropertyValue
  property ID: P639
  value: NM_002775
additional property: PropertyValue
  property ID: P644
  value: 124221041
additional property: PropertyValue
  property ID: P644
  value: 122458551
additional property: PropertyValue
  property ID: P645
  value: 124274424
additional property: PropertyValue
  property ID: P645
  value: 122514907
additional property: PropertyValue
  property ID: P646
  value: /m/03gx4_c
additional property: PropertyValue
  property ID: P684
  value: Htra1
additional property: PropertyValue
  property ID: P684
  value: Htra1
additional property: PropertyValue
  property ID: P684
  value: htra1b
additional property: PropertyValue
  property ID: P688
  value: HtrA serine peptidase 1
additional property: PropertyValue
  property ID: P692
  value: PBB GE HTRA1 201185 at fs.png
additional property: PropertyValue
  property ID: P703
  value: Homo sapiens
additional property: PropertyValue
  property ID: P704
  value: ENST00000420892
additional property: PropertyValue
  property ID: P704
  value: ENST00000368984
additional property: PropertyValue
  property ID: P704
  value: ENST00000648167
additional property: PropertyValue
  property ID: P1057
  value: human chromosome 10
additional property: PropertyValue
  property ID: P2293
  value: age related macular degeneration
additional property: PropertyValue
  property ID: P2293
  value: age related macular degeneration 7
additional property: PropertyValue
  property ID: P2293
  value: cerebral arteriopathy, autosomal dominant, with subcortical infarcts and leukoencephalopathy, type 2
additional property: PropertyValue
  property ID: P2548
  value: forward strand
additional property: PropertyValue
  property ID: P2888
  value: http://identifiers.org/ncbigene/5654
confidence:
  popularity graph score:
    score: 0.002
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 13
      unique citations norm: 0.005
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 13
  monthly pageviews: 0
  yearly pageviews: 20
  pageview trend:
    m: 2026-06
    v: 17
  pageview trend:
    m: 2026-05
    v: 3
  tier: established
claims:
  P18:
    value: Protein HTRA1 PDB 2JOA.png
    source count: 0
    confidence: 0.0
  P31:
    value: Q7187
    source count: 1
    confidence: 0.2
    value label: gene
  P279:
    value: Q20747295
    source count: 1
    confidence: 0.2
    value label: protein-coding gene
  P351:
    value: 5654
    source count: 1
    confidence: 0.2
  P353:
    value: HTRA1
    source count: 1
    confidence: 0.2
  P354:
    value: 9476
    source count: 1
    confidence: 0.2
  P492:
    value: 602194
    source count: 1
    confidence: 0.2
  P593:
    value: 31114
    source count: 1
    confidence: 0.2
  P594:
    value: ENSG00000166033
    source count: 1
    confidence: 0.2
  P639:
    value: NM_002775
    source count: 1
    confidence: 0.2
  P644:
    value: 124221041
    source count: 1
    confidence: 0.2
  P644:
    value: 122458551
    source count: 1
    confidence: 0.2
  P645:
    value: 124274424
    source count: 1
    confidence: 0.2
  P645:
    value: 122514907
    source count: 1
    confidence: 0.2
  P646:
    value: /m/03gx4_c
    source count: 0
    confidence: 0.0
  P684:
    value: Q18258324
    source count: 2
    confidence: 0.4
    value label: Htra1
  P684:
    value: Q24423931
    source count: 2
    confidence: 0.4
    value label: Htra1
  P684:
    value: Q29771660
    source count: 2
    confidence: 0.4
    value label: htra1b
  P684:
    value: Q29772783
    source count: 1
    confidence: 0.2
    value label: htra1a
  P688:
    value: Q21103357
    source count: 1
    confidence: 0.2
    value label: HtrA serine peptidase 1

value: PBB GE HTRA1 201185 at fs.png
source count: 0
confidence: 0.0

value: Q15978631
source count: 1
confidence: 0.2
value label: Homo sapiens

value: ENST00000420892
source count: 1
confidence: 0.2

value: ENST00000368984
source count: 1
confidence: 0.2

value: ENST00000648167
source count: 1
confidence: 0.2

value: Q840737
source count: 1
confidence: 0.2
value label: human chromosome 10

value: Q830308
source count: 1
confidence: 0.2
value label: age related macular degeneration

value: Q27437070
source count: 1
confidence: 0.2
value label: age related macular degeneration 7

value: Q32146338
source count: 2
confidence: 0.4
value label: cerebral arteriopathy, autosomal dominant, with subcortical infarcts and leukoencephalopathy, type 2

value: Q25324161
source count: 1
confidence: 0.2
value label: Cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy

value: Q22809680
source count: 1
confidence: 0.2
value label: forward strand

value: http://identifiers.org/ncbigene/5654
source count: 1
confidence: 0.2

value: C1825552
source count: 1
confidence: 0.2

value: 10q26.13
source count: 1
confidence: 0.2

value: Q66527398
source count: 1
confidence: 0.2
value label: tendon of biceps brachii

value: Q909882
source count: 1
confidence: 0.2
value label: glomerulus

value: Q30030409
source count: 1
confidence: 0.2
value label: metanephric glomerulus

value: Q66592966
source count: 1
confidence: 0.2
value label: Descending thoracic aorta

value: Q66592424
source count: 1
confidence: 0.2
value label: stromal cell of endometrium

value: 2780489581
source count: 0
confidence: 0.0

source: Phenocarta
stated in qid: Q22330995
retrieved: 2020-05-25

source: Open Targets Platform
stated in qid: Q113138000
retrieved: 2023-08-24

source: Open Targets Platform
stated in qid: Q113138000
retrieved: 2023-08-24

source: Bgee
stated in qid: Q54985720
retrieved: 2024-06-07

source: Orthologous MAtrix
stated in qid: Q7104801

source: Identifiers.org
stated in qid: Q16335166

source: Q20641742
stated in qid: Q20641742
retrieved: 2022-05-15

source: Online Mendelian Inheritance in Man
stated in qid: Q241953
retrieved: 2019-08-19

source: UniProt
stated in qid: Q905695
retrieved: 2017-07-06

source: UMLS 2023
stated in qid: Q118645236
retrieved: 2023-06-15

source: ensembl Release 106
stated in qid: Q111699881

source: Ensembl Release 87
stated in qid: Q27975061

source: HomoloGene build68
stated in qid: Q20976936

wikidata id: Q18030830
domain: gene
level: standard
html url: https://4ort.xyz/entity/htra1
markdown url: https://4ort.xyz/entity/htra1.md
facts url summary: https://4ort.xyz/entity/htra1/facts.json
facts url standard: https://4ort.xyz/entity/htra1/facts.json
facts url full: https://4ort.xyz/entity/htra1/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-04T19:07:23.301081Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T15:25:19.837860+00:00Z