# HtrA serine peptidase 2

> mammalian protein found in Mus musculus

**Wikidata**: [Q21981437](https://www.wikidata.org/wiki/Q21981437)  
**Source**: https://4ort.xyz/entity/htra-serine-peptidase-2-q21981437


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q9JIY5)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JIY5)
5. [HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JIY5)
6. [Hax1-mediated processing of HtrA2 by Parl allows survival of lymphocytes and neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JIY5)
7. [Mpv17l protects against mitochondrial oxidative stress and apoptosis by activation of Omi/HtrA2 protease.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JIY5)
8. [Inactivation of Omi/HtrA2 protease leads to the deregulation of mitochondrial Mulan E3 ubiquitin ligase and increased mitophagy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JIY5)
9. [Tim50, a component of the mitochondrial translocator, regulates mitochondrial integrity and cell death](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JIY5)
10. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JIY5&geneProductId=UniProtKB:Q9JIY5)
11. [The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JIY5&geneProductId=UniProtKB:Q9JIY5)
12. [Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JIY5&geneProductId=UniProtKB:Q9JIY5)
13. [A mitochondrial protein compendium elucidates complex I disease biology](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JIY5&geneProductId=UniProtKB:Q9JIY5)
14. [HOIL-1L interacting protein (HOIP) as an NF-kappaB regulating component of the CD40 signaling complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JIY5)
15. [The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JIY5)
16. [Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JIY5)
17. [A mitochondrial protein compendium elucidates complex I disease biology](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JIY5)
18. [mnd2: a new mouse model of inherited motor neuron disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JIY5)
19. [Neuroprotective role of the Reaper-related serine protease HtrA2/Omi revealed by targeted deletion in mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JIY5)
20. [Tissue-specific tumor suppressor activity of retinoblastoma gene homologs p107 and p130](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JIY5)
21. ensembl Release 106