# Hsp70 family ATPase KAR2 YJL034W

> fungal protein found in Saccharomyces cerevisiae S288c

**Wikidata**: [Q27551305](https://www.wikidata.org/wiki/Q27551305)  
**Source**: https://4ort.xyz/entity/hsp70-family-atpase-kar2-yjl034w


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P16474)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P16474&geneProductId=UniProtKB:P16474)
5. [Purification and characterization of BiP/Kar2 protein from Saccharomyces cerevisiae](http://www.ebi.ac.uk/QuickGO/annotations?protein=P16474&geneProductId=UniProtKB:P16474)
6. [Genetic evidence for a role of BiP/Kar2 that regulates Ire1 in response to accumulation of unfolded proteins.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P16474&geneProductId=UniProtKB:P16474)
7. [Futile protein folding cycles in the ER are terminated by the unfolded protein O-mannosylation pathway.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P16474&geneProductId=UniProtKB:P16474)
8. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16474)
9. [A luminal surveillance complex that selects misfolded glycoproteins for ER-associated degradation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16474)
10. [Proteome survey reveals modularity of the yeast cell machinery](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16474)
11. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16474)
12. [Purification and characterization of BiP/Kar2 protein from Saccharomyces cerevisiae](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16474)
13. [Genetic evidence for a role of BiP/Kar2 that regulates Ire1 in response to accumulation of unfolded proteins.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16474)
14. [Futile protein folding cycles in the ER are terminated by the unfolded protein O-mannosylation pathway.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16474)
15. [KAR2, a karyogamy gene, is the yeast homolog of the mammalian BiP/GRP78 gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16474)
16. [BiP and Sec63p are required for both co- and posttranslational protein translocation into the yeast endoplasmic reticulum](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16474)
17. [BiP acts as a molecular ratchet during posttranslational transport of prepro-alpha factor across the ER membrane](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16474)
18. [Molecular chaperones in the yeast endoplasmic reticulum maintain the solubility of proteins for retrotranslocation and degradation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P16474&geneProductId=UniProtKB:P16474)
19. [Genetic interactions between KAR7/SEC71, KAR8/JEM1, KAR5, and KAR2 during nuclear fusion in Saccharomyces cerevisiae](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16474)
20. [Cell wall 1,6-beta -glucan synthesis in Saccharomyces cerevisiae depends on ER glucosidases I and II, and the molecular chaperone BiP/Kar2p](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16474)
21. [Molecular chaperones in the yeast endoplasmic reticulum maintain the solubility of proteins for retrotranslocation and degradation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16474)
22. ensembl Release 106