# Hopscotch Dmel_CG1594

> protein found in Drosophila melanogaster

**Wikidata**: [Q51236137](https://www.wikidata.org/wiki/Q51236137)  
**Source**: https://4ort.xyz/entity/hopscotch-dmel-cg1594


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q24592)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24592)
5. [The roles of JAK/STAT signaling in Drosophila immune responses](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24592)
6. [Stripe-specific regulation of pair-rule genes by hopscotch, a putative Jak family tyrosine kinase in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24592)
7. [Drosophila SOCS36E negatively regulates JAK/STAT pathway signaling via two separable mechanisms.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24592)
8. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q24592&geneProductId=UniProtKB:Q24592)
9. [Mechanisms of JAK/STAT pathway negative regulation by the short coreceptor Eye Transformer/Latran.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24592)
10. [The JAK-STAT pathway in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24592)
11. [Polarized subcellular localization of Jak/STAT components is required for efficient signaling.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24592)
12. [Long-range effect of upd, a ligand for Jak/STAT pathway, on cell cycle in Drosophila eye development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24592)
13. [The Drosophila Jak kinase hopscotch is required for multiple developmental processes in the eye.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24592)
14. [Repression of Wasp by JAK/STAT signalling inhibits medial actomyosin network assembly and apical cell constriction in intercalating epithelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24592)
15. [The evolution and genetics of innate immunity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24592)
16. [The roles of JAK/STAT signaling in Drosophila immune responses](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q24592&geneProductId=UniProtKB:Q24592)
17. [The JAK/STAT signaling pathway is required for the initial choice of sexual identity in Drosophila melanogaster](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q24592&geneProductId=UniProtKB:Q24592)
18. [The fertile field of Drosophila Jak/STAT signalling](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q24592&geneProductId=UniProtKB:Q24592)
19. [Eye transformer is a negative regulator of Drosophila JAK/STAT signaling.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q24592&geneProductId=UniProtKB:Q24592)
20. [Marelle acts downstream of the Drosophila HOP/JAK kinase and encodes a protein similar to the mammalian STATs](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q24592&geneProductId=UniProtKB:Q24592)
21. [The JAK/STAT pathway and Drosophila development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24592)
22. [A gradient of JAK pathway activity patterns the anterior-posterior axis of the follicular epithelium.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q24592&geneProductId=UniProtKB:Q24592)
23. [Cyclin D-Cdk4 and cyclin E-Cdk2 regulate the Jak/STAT signal transduction pathway in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24592)
24. [Patterns and functions of STAT activation during Drosophila embryogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24592)
25. [Localized JAK/STAT signaling is required for oriented cell rearrangement in a tubular epithelium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24592)
26. [JAK/STAT signaling promotes regional specification by negatively regulating wingless expression in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24592)
27. [The JAK/STAT signaling pathway is required for the initial choice of sexual identity in Drosophila melanogaster](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24592)
28. [Cytokine signaling through the JAK/STAT pathway is required for long-term memory in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24592)
29. [Stem cell self-renewal specified by JAK-STAT activation in response to a support cell cue](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24592)
30. [Thicker than blood: conserved mechanisms in Drosophila and vertebrate hematopoiesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24592)
31. [A gradient of JAK pathway activity patterns the anterior-posterior axis of the follicular epithelium.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24592)
32. [Drosophila follicle cells are patterned by multiple levels of Notch signaling and antagonism between the Notch and JAK/STAT pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24592)
33. [Drosophila linker histone H1 coordinates STAT-dependent organization of heterochromatin and suppresses tumorigenesis caused by hyperactive JAK-STAT signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24592)
34. [The Friend of GATA protein U-shaped functions as a hematopoietic tumor suppressor in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24592)
35. [Genetic manipulation of AML1-ETO-induced expansion of hematopoietic precursors in a Drosophila model](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24592)
36. [The stem-cell niche theory: lessons from flies](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24592)
37. [The Hopscotch Jak kinase requires the Raf pathway to promote blood cell activation and differentiation in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24592)
38. [Regulation of Circadian Behavioral Output via a MicroRNA-JAK/STAT Circuit](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24592)
39. [A directed screen for genes involved in Drosophila blood cell activation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q24592&geneProductId=UniProtKB:Q24592)
40. [Broad RNA interference-mediated antiviral immunity and virus-specific inducible responses in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24592)
41. [The Jak-STAT signaling pathway is required but not sufficient for the antiviral response of drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24592)
42. [Eye transformer is a negative regulator of Drosophila JAK/STAT signaling.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24592)
43. [Marelle acts downstream of the Drosophila HOP/JAK kinase and encodes a protein similar to the mammalian STATs](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24592)
44. [Identification of JAK/STAT signalling components by genome-wide RNA interference.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24592)
45. [JAK/STAT controls organ size and fate specification by regulating morphogen production and signalling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24592)
46. ensembl Release 106