# Homeostatic iron regulator

> mammalian protein found in Mus musculus

**Wikidata**: [Q21436500](https://www.wikidata.org/wiki/Q21436500)  
**Source**: https://4ort.xyz/entity/homeostatic-iron-regulator-q21436500


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P70387)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70387)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P70387&geneProductId=UniProtKB:P70387)
6. [Hereditary hemochromatosis protein, HFE, interaction with transferrin receptor 2 suggests a molecular mechanism for mammalian iron sensing](http://www.ebi.ac.uk/QuickGO/annotations?protein=P70387&geneProductId=UniProtKB:P70387)
7. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=P70387&geneProductId=UniProtKB:P70387)
8. [Hereditary hemochromatosis protein, HFE, interaction with transferrin receptor 2 suggests a molecular mechanism for mammalian iron sensing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70387)
9. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70387)
10. [Contribution of Hfe expression in macrophages to the regulation of hepatic hepcidin levels and iron loading](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70387)
11. [Enhanced erythropoiesis in Hfe-KO mice indicates a role for Hfe in the modulation of erythroid iron homeostasis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70387)
12. [Smad6 and Smad7 are co-regulated with hepcidin in mouse models of iron overload](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70387)
13. [Multigenic control of hepatic iron loading in a murine model of hemochromatosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70387)
14. [Mechanism of increased iron absorption in murine model of hereditary hemochromatosis: increased duodenal expression of the iron transporter DMT1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70387)
15. [HFE interacts with the BMP type I receptor ALK3 to regulate hepcidin expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70387)
16. [Mechanism of increased iron absorption in murine model of hereditary hemochromatosis: increased duodenal expression of the iron transporter DMT1](http://www.ebi.ac.uk/QuickGO/annotations?protein=P70387&geneProductId=UniProtKB:P70387)
17. ensembl Release 106