# Homeobox protein OTX2

> mouse protein (annotated by UniProtKB/Swiss-Prot P80206)

**Wikidata**: [Q21985186](https://www.wikidata.org/wiki/Q21985186)  
**Source**: https://4ort.xyz/entity/homeobox-protein-otx2


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P80206)
3. [Swiss-Prot](http://www.uniprot.org/uniprot/P80206.txt?version=124)
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P80206)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P80206&geneProductId=UniProtKB:P80206)
6. [Gbx2 and Otx2 interact with the WD40 domain of Groucho/Tle corepressors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P80206)
7. [Otx2 regulates the extent, identity and fate of neuronal progenitor domains in the ventral midbrain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P80206)
8. [Functional analysis of transcriptional repressor Otx3/Dmbx1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P80206)
9. [Lhx1 functions together with Otx2, Foxa2, and Ldb1 to govern anterior mesendoderm, node, and midline development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P80206)
10. [The subcellular localization of Otx2 is cell-type specific and developmentally regulated in the mouse retina](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P80206)
11. [Transcriptional regulatory networks in epiblast cells and during anterior neural plate development as modeled in epiblast stem cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P80206)
12. [Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P80206)
13. [The Mammalian DM Domain Transcription Factor Dmrta2 Is Required for Early Embryonic Development of the Cerebral Cortex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P80206)
14. [Otx2 and Otx1 protect diencephalon and mesencephalon from caudalization into metencephalon during early brain regionalization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P80206)
15. [Otx2 homeobox gene controls retinal photoreceptor cell fate and pineal gland development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P80206)
16. [Complementary functions of Otx2 and Cripto in initial patterning of mouse epiblast](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P80206)
17. [Nkx6-1 controls the identity and fate of red nucleus and oculomotor neurons in the mouse midbrain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P80206)
18. [Defects of the body plan of mutant embryos lacking Lim1, Otx2 or Hnf3beta activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P80206)
19. [Otx2 regulates subtype specification and neurogenesis in the midbrain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P80206)
20. [Regionalisation of anterior neuroectoderm and its competence in responding to forebrain and midbrain inducing activities depend on mutual antagonism between OTX2 and GBX2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P80206)
21. [Otx dose-dependent integrated control of antero-posterior and dorso-ventral patterning of midbrain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P80206)
22. [Otx1 and Otx2 activities are required for the normal development of the mouse inner ear](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P80206)
23. [Regulation of Otx2 expression and its functions in mouse epiblast and anterior neuroectoderm](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P80206)
24. [Emx2 and Pax6 function in cooperation with Otx2 and Otx1 to develop caudal forebrain primordium that includes future archipallium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P80206)
25. [OTX2 Transcription Factor Controls Regional Patterning within the Medial Ganglionic Eminence and Regional Identity of the Septum](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P80206)
26. [A Wnt1-regulated genetic network controls the identity and fate of midbrain-dopaminergic progenitors in vivo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P80206)
27. [Regulation of Otx2 expression and its functions in mouse forebrain and midbrain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P80206)
28. [Murine cerberus homologue mCer-1: a candidate anterior patterning molecule](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P80206)
29. [Cloning and characterization of mr-s, a novel SAM domain protein, predominantly expressed in retinal photoreceptor cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P80206)
30. [miRNA 34a, 100, and 137 modulate differentiation of mouse embryonic stem cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P80206)