# HNF1 homeobox B

> mammalian protein found in Mus musculus

**Wikidata**: [Q21983332](https://www.wikidata.org/wiki/Q21983332)  
**Source**: https://4ort.xyz/entity/hnf1-homeobox-b-q21983332


## References

1. UniProt
2. Q20641742
3. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27889&geneProductId=UniProtKB:P27889)
4. [Hepatocyte nuclear factor 1 alpha controls renal expression of the Npt1-Npt4 anionic transporter locus](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27889&geneProductId=UniProtKB:P27889)
5. [HNF1beta/TCF2 mutations impair transactivation potential through altered co-regulator recruitment](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27889&geneProductId=UniProtKB:P27889)
6. [The vHNF1 homeodomain protein establishes early rhombomere identity by direct regulation of Kreisler expression](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27889&geneProductId=UniProtKB:P27889)
7. [LFB3, a heterodimer-forming homeoprotein of the LFB1 family, is expressed in specialized epithelia](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27889&geneProductId=UniProtKB:P27889)
8. [Role of the hepatocyte nuclear factor-1beta (HNF-1beta) C-terminal domain in Pkhd1 (ARPKD) gene transcription and renal cystogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27889&geneProductId=UniProtKB:P27889)
9. [Mutation of hepatocyte nuclear factor-1beta inhibits Pkhd1 gene expression and produces renal cysts in mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27889&geneProductId=UniProtKB:P27889)
10. [HNF1beta/TCF2 mutations impair transactivation potential through altered co-regulator recruitment](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27889)
11. [Hepatocyte nuclear factor 1 inactivation results in hepatic dysfunction, phenylketonuria, and renal Fanconi syndrome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27889)
12. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27889)
13. [Hnf6 and Tcf2 (MODY5) are linked in a gene network operating in a precursor cell domain of the embryonic pancreas](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27889)
14. [Expression patterns of vHNF1 and HNF1 homeoproteins in early postimplantation embryos suggest distinct and sequential developmental roles](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27889)
15. [Mutation of hepatocyte nuclear factor-1beta inhibits Pkhd1 gene expression and produces renal cysts in mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27889)
16. [LFB3, a heterodimer-forming homeoprotein of the LFB1 family, is expressed in specialized epithelia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27889)
17. [Plasticity and expanding complexity of the hepatic transcription factor network during liver development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27889)
18. [Hepatic nuclear factor 1 (HNF1) shows a wider distribution than products of its known target genes in developing mouse](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27889)
19. [Role of the hepatocyte nuclear factor-1beta (HNF-1beta) C-terminal domain in Pkhd1 (ARPKD) gene transcription and renal cystogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27889)
20. [HNF-1 alpha and HNF-1 beta (vHNF-1) share dimerization and homeo domains, but not activation domains, and form heterodimers in vitro](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27889)
21. [The vHNF1 homeodomain protein establishes early rhombomere identity by direct regulation of Kreisler expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27889)
22. [vHNF1 functions in distinct regulatory circuits to control ureteric bud branching and early nephrogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27889&geneProductId=UniProtKB:P27889)
23. [Hepatocyte nuclear factor 1 alpha controls renal expression of the Npt1-Npt4 anionic transporter locus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27889)
24. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27889)
25. [vHNF1 functions in distinct regulatory circuits to control ureteric bud branching and early nephrogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27889)
26. [Hepatic nuclear factor 1 (HNF1) shows a wider distribution than products of its known target genes in developing mouse](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27889&geneProductId=UniProtKB:P27889)
27. [Role of TIF1alpha as a modulator of embryonic transcription in the mouse zygote](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27889&geneProductId=UniProtKB:P27889)
28. [Hepatocyte nuclear factor 1 inactivation results in hepatic dysfunction, phenylketonuria, and renal Fanconi syndrome](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27889&geneProductId=UniProtKB:P27889)
29. [Expression patterns of vHNF1 and HNF1 homeoproteins in early postimplantation embryos suggest distinct and sequential developmental roles](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27889&geneProductId=UniProtKB:P27889)
30. [HNF-1 alpha and HNF-1 beta (vHNF-1) share dimerization and homeo domains, but not activation domains, and form heterodimers in vitro](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27889&geneProductId=UniProtKB:P27889)
31. [HNF1alpha is involved in tissue-specific regulation of CFTR gene expression](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27889&geneProductId=UniProtKB:P27889)
32. [Cystic renal neoplasia following conditional inactivation of apc in mouse renal tubular epithelium](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27889&geneProductId=UniProtKB:P27889)
33. [Cardiomyocyte-specific Bcl-2 overexpression attenuates ischemia-reperfusion injury, immune response during acute rejection, and graft coronary artery disease](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27889&geneProductId=UniProtKB:P27889)
34. [Cardiomyocyte-specific Bcl-2 overexpression attenuates ischemia-reperfusion injury, immune response during acute rejection, and graft coronary artery disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27889)
35. [Role of TIF1alpha as a modulator of embryonic transcription in the mouse zygote](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27889)
36. [HNF1alpha is involved in tissue-specific regulation of CFTR gene expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27889)
37. [Cystic renal neoplasia following conditional inactivation of apc in mouse renal tubular epithelium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27889)
38. [Hepatic Notch2 deficiency leads to bile duct agenesis perinatally and secondary bile duct formation after weaning](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27889)
39. [Variant hepatocyte nuclear factor 1 is required for visceral endoderm specification](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27889)
40. [Crucial role of vHNF1 in vertebrate hepatic specification](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27889)
41. [Essential role for the homeoprotein vHNF1/HNF1beta in visceral endoderm differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27889)
42. [Shifting boundaries of retinoic acid activity control hindbrain segmental gene expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27889)
43. [Selective deletion of the Hnf1beta (MODY5) gene in beta-cells leads to altered gene expression and defective insulin release](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27889&geneProductId=UniProtKB:P27889)
44. [Selective deletion of the Hnf1beta (MODY5) gene in beta-cells leads to altered gene expression and defective insulin release](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27889)
45. [Which FGF ligands are involved in lens induction?](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27889)
46. [HNF1B controls proximal-intermediate nephron segment identity in vertebrates by regulating Notch signalling components and Irx1/2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27889)
47. [Crucial role of vHNF1 in vertebrate hepatic specification](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27889&geneProductId=UniProtKB:P27889)
48. ensembl Release 106