# HNF1 homeobox A

> mammalian protein found in Mus musculus

**Wikidata**: [Q21983331](https://www.wikidata.org/wiki/Q21983331)  
**Source**: https://4ort.xyz/entity/hnf1-homeobox-a-q21983331


## References

1. UniProt
2. Q20641742
3. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22361)
4. [High-resolution structure of the HNF-1alpha dimerization domain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22361)
5. [Cohesin regulates tissue-specific expression by stabilizing highly occupied cis-regulatory modules](http://www.ebi.ac.uk/QuickGO/annotations?protein=P22361&geneProductId=UniProtKB:P22361)
6. [HNF1alpha controls renal glucose reabsorption in mouse and man.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22361)
7. [Small Heterodimer Partner Regulates Circadian Cytochromes p450 and Drug-Induced Hepatotoxicity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22361)
8. [Role of TIF1alpha as a modulator of embryonic transcription in the mouse zygote](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22361)
9. [Biochemical and structural basis for partially redundant enzymatic and transcriptional functions of DCoH and DCoH2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22361)
10. [Hepatocyte nuclear factor 1 inactivation results in hepatic dysfunction, phenylketonuria, and renal Fanconi syndrome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22361)
11. [A nutrient‐sensitive interaction between Sirt1 and HNF‐1α regulates Crp expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22361)
12. [Characterization of a Cofactor That Regulates Dimerization of a Mammalian Homeodomain Protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22361)
13. [Hepatocyte nuclear factor 1 alpha controls renal expression of the Npt1-Npt4 anionic transporter locus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22361)
14. [Hepatocyte nuclear factor-1alpha is an essential regulator of bile acid and plasma cholesterol metabolism](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22361)
15. [Hepatocyte nuclear factors 1alpha and 4alpha control expression of proline oxidase in adult liver](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22361)
16. [Mutation of hepatocyte nuclear factor-1beta inhibits Pkhd1 gene expression and produces renal cysts in mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22361)
17. [Expression patterns of vHNF1 and HNF1 homeoproteins in early postimplantation embryos suggest distinct and sequential developmental roles](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22361)
18. [HNF-1 alpha and HNF-1 beta (vHNF-1) share dimerization and homeo domains, but not activation domains, and form heterodimers in vitro](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22361)
19. [Hepatocyte nuclear factor-1alpha is required for expression but dispensable for histone acetylation of the lactase-phlorizin hydrolase gene in vivo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22361)
20. [Abnormal gene expression and regulation in the liver of jvs mice with systemic carnitine deficiency](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22361)
21. [Molecular cloning, functional expression, and chromosomal localization of mouse hepatocyte nuclear factor 1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22361)
22. [A molecular link between the common phenotypes of type 1 glycogen storage disease and HNF1alpha-null mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22361)
23. [Plasticity and expanding complexity of the hepatic transcription factor network during liver development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22361)
24. [Hnf6 and Tcf2 (MODY5) are linked in a gene network operating in a precursor cell domain of the embryonic pancreas](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22361)
25. [MFH-1, a new member of the fork head domain family, is expressed in developing mesenchyme](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22361)
26. [Hepatic nuclear factor 1 (HNF1) shows a wider distribution than products of its known target genes in developing mouse](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22361)
27. [Hepatocyte nuclear factor-1 acts as an accessory factor to enhance the inhibitory action of insulin on mouse glucose-6-phosphatase gene transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22361)
28. [LFB3, a heterodimer-forming homeoprotein of the LFB1 family, is expressed in specialized epithelia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22361)
29. [The fetoprotein transcription factor (FTF) gene is essential to embryogenesis and cholesterol homeostasis and is regulated by a DR4 element](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22361)
30. [Characterization of a Cofactor That Regulates Dimerization of a Mammalian Homeodomain Protein](http://www.ebi.ac.uk/QuickGO/annotations?protein=P22361&geneProductId=UniProtKB:P22361)
31. [Role of TIF1alpha as a modulator of embryonic transcription in the mouse zygote](http://www.ebi.ac.uk/QuickGO/annotations?protein=P22361&geneProductId=UniProtKB:P22361)
32. [Hepatocyte nuclear factor 1 inactivation results in hepatic dysfunction, phenylketonuria, and renal Fanconi syndrome](http://www.ebi.ac.uk/QuickGO/annotations?protein=P22361&geneProductId=UniProtKB:P22361)
33. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P22361&geneProductId=UniProtKB:P22361)
34. [Hepatocyte nuclear factor 1 alpha controls renal expression of the Npt1-Npt4 anionic transporter locus](http://www.ebi.ac.uk/QuickGO/annotations?protein=P22361&geneProductId=UniProtKB:P22361)
35. [LFB3, a heterodimer-forming homeoprotein of the LFB1 family, is expressed in specialized epithelia](http://www.ebi.ac.uk/QuickGO/annotations?protein=P22361&geneProductId=UniProtKB:P22361)
36. [Hepatocyte nuclear factor-1alpha is an essential regulator of bile acid and plasma cholesterol metabolism](http://www.ebi.ac.uk/QuickGO/annotations?protein=P22361&geneProductId=UniProtKB:P22361)
37. [Molecular cloning, functional expression, and chromosomal localization of mouse hepatocyte nuclear factor 1](http://www.ebi.ac.uk/QuickGO/annotations?protein=P22361&geneProductId=UniProtKB:P22361)
38. [A molecular link between the common phenotypes of type 1 glycogen storage disease and HNF1alpha-null mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=P22361&geneProductId=UniProtKB:P22361)
39. [HNF-1 alpha and HNF-1 beta (vHNF-1) share dimerization and homeo domains, but not activation domains, and form heterodimers in vitro](http://www.ebi.ac.uk/QuickGO/annotations?protein=P22361&geneProductId=UniProtKB:P22361)
40. [HNF1alpha controls renal glucose reabsorption in mouse and man.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P22361&geneProductId=UniProtKB:P22361)
41. [Mutation of hepatocyte nuclear factor-1beta inhibits Pkhd1 gene expression and produces renal cysts in mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=P22361&geneProductId=UniProtKB:P22361)
42. [Hepatic nuclear factor 1-alpha directs nucleosomal hyperacetylation to its tissue-specific transcriptional targets](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22361)
43. [Anks4b, a novel target of HNF4α protein, interacts with GRP78 protein and regulates endoplasmic reticulum stress-induced apoptosis in pancreatic β-cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22361)
44. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22361)
45. [Cohesin regulates tissue-specific expression by stabilizing highly occupied cis-regulatory modules](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22361)
46. [Wnt3a-/--like phenotype and limb deficiency in Lef1(-/-)Tcf1(-/-) mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22361)
47. [Immunological characterization of hepatocyte nuclear factor 1 protein: appearance of hepatocyte nuclear factor 1 protein in developing mouse embryos](http://www.ebi.ac.uk/QuickGO/annotations?protein=P22361&geneProductId=UniProtKB:P22361)
48. [Expression patterns of vHNF1 and HNF1 homeoproteins in early postimplantation embryos suggest distinct and sequential developmental roles](http://www.ebi.ac.uk/QuickGO/annotations?protein=P22361&geneProductId=UniProtKB:P22361)
49. [Hepatocyte nuclear factor-1alpha is required for expression but dispensable for histone acetylation of the lactase-phlorizin hydrolase gene in vivo](http://www.ebi.ac.uk/QuickGO/annotations?protein=P22361&geneProductId=UniProtKB:P22361)
50. [Role of the hepatocyte nuclear factor-1beta (HNF-1beta) C-terminal domain in Pkhd1 (ARPKD) gene transcription and renal cystogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P22361&geneProductId=UniProtKB:P22361)