# Histone deacetylase RPD3 YNL330C

> fungal protein found in Saccharomyces cerevisiae S288c

**Wikidata**: [Q27548560](https://www.wikidata.org/wiki/Q27548560)  
**Source**: https://4ort.xyz/entity/histone-deacetylase-rpd3-ynl330c


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P32561)
3. Q20641742
4. [The MAPK Hog1 recruits Rpd3 histone deacetylase to activate osmoresponsive genes.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32561)
5. [Transcriptional repression by UME6 involves deacetylation of lysine 5 of histone H4 by RPD3](http://www.ebi.ac.uk/QuickGO/annotations?protein=P32561&geneProductId=UniProtKB:P32561)
6. [A conserved motif common to the histone acetyltransferase Esa1 and the histone deacetylase Rpd3.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P32561&geneProductId=UniProtKB:P32561)
7. [Histone deacetylase activity of Rpd3 is important for transcriptional repression in vivo](http://www.ebi.ac.uk/QuickGO/annotations?protein=P32561&geneProductId=UniProtKB:P32561)
8. [HDA1 and RPD3 are members of distinct yeast histone deacetylase complexes that regulate silencing and transcription](http://www.ebi.ac.uk/QuickGO/annotations?protein=P32561&geneProductId=UniProtKB:P32561)
9. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P32561&geneProductId=UniProtKB:P32561)
10. [Repression by Ume6 involves recruitment of a complex containing Sin3 corepressor and Rpd3 histone deacetylase to target promoters](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32561)
11. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32561)
12. [Raf60, a novel component of the Rpd3 histone deacetylase complex required for Rpd3 activity in Saccharomyces cerevisiae](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32561)
13. [Eaf5/7/3 form a functionally independent NuA4 submodule linked to RNA polymerase II-coupled nucleosome recycling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32561)
14. [The yeast Snt2 protein coordinates the transcriptional response to hydrogen peroxide-mediated oxidative stress](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32561)
15. [Identification of two CyP-40-like cyclophilins in Saccharomyces cerevisiae, one of which is required for normal growth](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32561)
16. [Ssn6-Tup1 interacts with class I histone deacetylases required for repression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32561)
17. [Analyzing chromatin remodeling complexes using shotgun proteomics and normalized spectral abundance factors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32561)
18. [Defining the budding yeast chromatin‐associated interactome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32561)
19. [Tup1-Ssn6 interacts with multiple class I histone deacetylases in vivo.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32561)
20. [Proteome survey reveals modularity of the yeast cell machinery](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32561)
21. [Histone deacetylase activity of Rpd3 is important for transcriptional repression in vivo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32561)
22. [A conserved motif common to the histone acetyltransferase Esa1 and the histone deacetylase Rpd3.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32561)
23. [Transcriptional repression by UME6 involves deacetylation of lysine 5 of histone H4 by RPD3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32561)
24. [HDA1 and RPD3 are members of distinct yeast histone deacetylase complexes that regulate silencing and transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32561)
25. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32561)
26. [Histone H3 methylation by Set2 directs deacetylation of coding regions by Rpd3S to suppress spurious intragenic transcription](http://www.ebi.ac.uk/QuickGO/annotations?protein=P32561&geneProductId=UniProtKB:P32561)
27. [Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex](http://www.ebi.ac.uk/QuickGO/annotations?protein=P32561&geneProductId=UniProtKB:P32561)
28. [Stable incorporation of sequence specific repressors Ash1 and Ume6 into the Rpd3L complex](http://www.ebi.ac.uk/QuickGO/annotations?protein=P32561&geneProductId=UniProtKB:P32561)
29. [Cmr1/WDR76 defines a nuclear genotoxic stress body linking genome integrity and protein quality control](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32561)
30. [A Large Protein Complex Containing the Yeast Sin3p and Rpd3p Transcriptional Regulators](http://www.ebi.ac.uk/QuickGO/annotations?protein=P32561&geneProductId=UniProtKB:P32561)
31. [Histone H3 methylation by Set2 directs deacetylation of coding regions by Rpd3S to suppress spurious intragenic transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32561)
32. [Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32561)
33. [A Large Protein Complex Containing the Yeast Sin3p and Rpd3p Transcriptional Regulators](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32561)
34. [Stable incorporation of sequence specific repressors Ash1 and Ume6 into the Rpd3L complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32561)
35. [Chromatin Central: towards the comparative proteome by accurate mapping of the yeast proteomic environment](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32561)
36. [Silencing near tRNA genes is nucleosome-mediated and distinct from boundary element function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32561)
37. [Histone H3K4 and K36 methylation, Chd1 and Rpd3S oppose the functions of Saccharomyces cerevisiae Spt4-Spt5 in transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32561)
38. [Activation of the G2/M-specific gene CLB2 requires multiple cell cycle signals](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32561)
39. [Function and molecular mechanism of acetylation in autophagy regulation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32561)
40. [Genome-wide replication profiles indicate an expansive role for Rpd3L in regulating replication initiation timing or efficiency, and reveal genomic loci of Rpd3 function in Saccharomyces cerevisiae](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32561)
41. [Histone acetylation regulates the time of replication origin firing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32561)
42. [The Rpd3-Sin3 histone deacetylase regulates replication timing and enables intra-S origin control in Saccharomyces cerevisiae](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32561)
43. [Nutrient starvation promotes condensin loading to maintain rDNA stability](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32561)
44. [H4 acetylation does not replace H3 acetylation in chromatin remodelling and transcription activation of Adr1-dependent genes.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32561)
45. [The Rpd3L HDAC complex is essential for the heat stress response in yeast.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32561)
46. [The unfolded protein response represses differentiation through the RPD3-SIN3 histone deacetylase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32561)
47. [Transcriptional Regulation by Pho23 Modulates the Frequency of Autophagosome Formation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32561)
48. [The roles of the catalytic and noncatalytic activities of Rpd3L and Rpd3S in the regulation of gene transcription in yeast](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32561)
49. [Direct role for the Rpd3 complex in transcriptional induction of the anaerobic DAN/TIR genes in yeast](http://www.ebi.ac.uk/QuickGO/annotations?protein=P32561&geneProductId=UniProtKB:P32561)
50. [Histone deacetylases RPD3 and HOS2 regulate the transcriptional activation of DNA damage-inducible genes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P32561&geneProductId=UniProtKB:P32561)